HitPredict

Interactor 1: TF2AA (P52655)
Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)]
Gene: GTF2A1

Interactor 2: TBPL1 (P62380)
TATA box-binding protein-like 1 (TBP-like 1) (21 kDa TBP-like protein) (Second TBP of unique DNA protein) (STUD) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (TBP-related protein)
Gene: TBPL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 17353931, 32296183, 10570139, 26186194, 28514442, 33961781, 17643375, unassigned1304, 24835508
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TBP~TFIIA
Common GO terms GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0005672 - transcription factor TFIIA complex
GO:0006366 - transcription by RNA polymerase II
GO:0016251 - RNA polymerase II general transcription initiation factor activity
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 376
Hs

1 186
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Last updated: 15 Jul 2024