Protein: TM59L
Transmembrane protein 59-like (Brain-specific membrane-anchored protein)

Gene: TM59L, TMEM59L
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q9UK28

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1460898

ITM2B
Integral membrane protein 2B

3

0

High-throughput

0.638

High

586195

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

2

3

High-throughput

0.628

High

1460895

PCDGG
Protocadherin gamma-B4

2

2

High-throughput

0.628

High

1449739

GINM1
Glycoprotein integral membrane protein 1

2

0

High-throughput

0.585

High

855396

5HT3A
5-hydroxytryptamine receptor 3A

2

2

High-throughput

0.574

High

380378

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

2

High-throughput

0.536

High

749820

CADH5
Cadherin-5

1

1

High-throughput

0.536

High

1159248

SGCA
Alpha-sarcoglycan

1

1

High-throughput

0.536

High

1316011

NRSN1
Neurensin-1

1

1

High-throughput

0.536

High

1414302

ABHEA
Protein ABHD14A

1

1

High-throughput

0.536

High

1460896

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

1

High-throughput

0.536

High

723272

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

0

High-throughput

0.513

High

1417279

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

127822

CORT
Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]

1

1

High-throughput

0.489

High

438919

CD1A
T-cell surface glycoprotein CD1a

1

4

High-throughput

0.489

High

548148

PSPC
Surfactant protein C

1

1

High-throughput

0.489

High

731909

CEAM8
Cell adhesion molecule CEACAM8

1

1

High-throughput

0.489

High

1048808

ACHE
Acetylcholine receptor subunit epsilon

1

1

High-throughput

0.489

High

1180980

HFE
Hereditary hemochromatosis protein

1

1

High-throughput

0.489

High

1249964

I20RB
Interleukin-20 receptor subunit beta

1

1

High-throughput

0.489

High

1292602

IFNE
Interferon epsilon

1

1

High-throughput

0.489

High

1330500

LRC52
Leucine-rich repeat-containing protein 52

1

2

High-throughput

0.489

High

1360213

5HT3C
5-hydroxytryptamine receptor 3C

1

2

High-throughput

0.489

High

1434668

SG196
Protein O-mannose kinase

1

1

High-throughput

0.489

High

1438718

CRLF2
Cytokine receptor-like factor 2

1

1

High-throughput

0.489

High

1460892

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.489

High

1460899

PCDB1
Protocadherin beta-1

1

3

High-throughput

0.489

High

1460900

ST14
Suppressor of tumorigenicity 14 protein

1

2

High-throughput

0.489

High

1208679

NTCP5
Sodium/bile acid cotransporter 5

1

1

High-throughput

0.445

High

1338007

ZNT7
Zinc transporter 7

1

4

High-throughput

0.445

High

1346827

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

4

High-throughput

0.445

High

1417625

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

1

High-throughput

0.445

High

1047336

P
P protein

1

1

High-throughput

0.407

High

1419166

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

1

High-throughput

0.407

High

1460893

YLAT1
Y+L amino acid transporter 1

1

1

High-throughput

0.407

High

1351242

MCLN3
Mucolipin-3

3

0

High-throughput

0.347

High

1460894

AT1B4
Protein ATP1B4

3

0

High-throughput

0.347

High

761101

GBRA3
Gamma-aminobutyric acid receptor subunit alpha-3

2

0

High-throughput

0.328

High

1198766

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

253460

CST8
Cystatin-8

1

0

High-throughput

0.279

Low

460287

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

0

High-throughput

0.279

Low

590357

MUC1
Mucin-1

1

0

High-throughput

0.279

Low

749418

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

1101441

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1460897

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.279

Low

862534

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.261

Low

903277

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025