HitPredict

Interactor 1: ZN143 (P52747)
Zinc finger protein 143 (SPH-binding factor) (Selenocysteine tRNA gene transcription-activating factor) (hStaf)
Gene: ZNF143

Interactor 2: LMO3 (Q8TAP4)
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3)
Gene: LMO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 145
+	Hs
		638489 ZN143_HUMAN (1-638): 3.15e-177: 519: 100.00		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Hs
		735118 ZNF76_HUMAN (45-631): 8.7e-160: 472: 55.78		LHX6_HUMAN (3-137): 8.85e-42: 143: 36.30
+	Hs
		638484 ZNF76_HUMAN (45-631): 8.7e-160: 472: 55.78		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Hs
		735087 ZNF76_HUMAN (45-631): 8.7e-160: 472: 55.78		LHX4_HUMAN (72-144): 4.55e-12: 63.8: 19.18
+	Hs
		735114 ZNF76_HUMAN (45-631): 8.7e-160: 472: 55.78		LHX3_HUMAN (4-68): 2.41e-11: 61.9: 21.21
+	Hs
		855972 ZN135_HUMAN (309-638): 2.21e-122: 379: 23.67		LMO4_HUMAN (11-142): 3.16e-41: 136: 50.76
+	Hs
		638487 ZNF84_HUMAN (61-355): 5.96e-92: 301: 21.48		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Hs
		846679 ZNF84_HUMAN (61-355): 5.96e-92: 301: 21.48		LMO3_HUMAN (1-145): 3.61e-37: 125: 100.00
+	Hs
		638344 ZNF34_HUMAN (294-634): 1.72e-59: 210: 18.37		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Hs
		903758 ZN675_HUMAN (172-481): 1.4e-57: 205: 26.52		LMO4_HUMAN (11-142): 3.16e-41: 136: 50.76