Protein: FRMD5
FERM domain-containing protein 5

Gene: FRMD5
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q7Z6J6

Gene Ontology (top 5):
GO:0005178 - integrin binding
GO:0005856 - cytoskeleton
GO:0005912 - adherens junction
GO:0008092 - cytoskeletal protein binding
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

557362

SRC
Proto-oncogene tyrosine-protein kinase Src

1

19

High-throughput

0.691

High

212439

SPIT2
Kunitz-type protease inhibitor 2

4

7

High-throughput

0.691

High

60731

F234B
Protein FAM234B

3

1

High-throughput

0.675

High

1280084

CLC2D
C-type lectin domain family 2 member D

2

5

High-throughput

0.628

High

1164050

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

7

High-throughput

0.618

High

1280065

STX12
Syntaxin-12

3

7

High-throughput

0.609

High

391315

FRIL
Ferritin light chain

2

0

High-throughput

0.576

High

1186405

ASTRB
Protein Aster-B

2

0

High-throughput

0.576

High

484173

PGFRB
Platelet-derived growth factor receptor beta

1

20

High-throughput

0.575

High

1144046

TEBP
Prostaglandin E synthase 3

2

1

High-throughput

0.574

High

1280070

NRCAM
Neuronal cell adhesion molecule

2

8

High-throughput

0.574

High

1280090

PCDAC
Protocadherin alpha-12

2

3

High-throughput

0.574

High

1280095

PCDC2
Protocadherin alpha-C2

2

3

High-throughput

0.574

High

612093

ITB5
Integrin beta-5

1

6

Small-scale

0.561

High

638209

S1PR1
Sphingosine 1-phosphate receptor 1

2

5

High-throughput

0.549

High

1280094

PCDA8
Protocadherin alpha-8

2

3

High-throughput

0.549

High

62138

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

5

High-throughput

0.536

High

157557

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.536

High

254173

CTND1
Catenin delta-1

1

10

Small-scale

0.536

High

475389

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.536

High

531095

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

1

High-throughput

0.536

High

691185

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

718418

CD6
T-cell differentiation antigen CD6

1

8

High-throughput

0.536

High

727869

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.536

High

730006

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

966540

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

1207954

COL12
Collectin-12

1

3

High-throughput

0.536

High

1213632

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

3

High-throughput

0.536

High

1280087

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.536

High

1280088

CLC4E
C-type lectin domain family 4 member E

1

4

High-throughput

0.536

High

1280091

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

7

High-throughput

0.536

High

1280092

PCDB3
Protocadherin beta-3

1

2

High-throughput

0.536

High

1106276

ROCK1
Rho-associated protein kinase 1

1

7

Small-scale

0.515

High

295600

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.513

High

1159153

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.513

High

1259186

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.513

High

1280068

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

1280081

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.513

High

66445

ASB14
Ankyrin repeat and SOCS box protein 14

1

14

High-throughput

0.489

High

317344

ACL6B
Actin-like protein 6B

1

5

High-throughput

0.489

High

341325

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.489

High

351918

S1PR4
Sphingosine 1-phosphate receptor 4

1

6

High-throughput

0.489

High

1049494

1433F
14-3-3 protein eta

1

20

High-throughput

0.489

High

1249802

BTNL9
Butyrophilin-like protein 9

1

3

High-throughput

0.489

High

1280074

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.489

High

1280077

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.489

High

1280078

LPAR2
Lysophosphatidic acid receptor 2

1

5

High-throughput

0.489

High

1280085

BTNL2
Butyrophilin-like protein 2

1

11

High-throughput

0.489

High

1280086

HSPB8
Heat shock protein beta-8

1

4

High-throughput

0.489

High

1280089

CLC4A
C-type lectin domain family 4 member A

1

3

High-throughput

0.489

High

1280096

IRAG1
Inositol 1,4,5-triphosphate receptor associated 1

1

1

High-throughput

0.489

High

1280097

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.489

High

532717

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

1254426

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

357952

CYB5
Cytochrome b5

1

1

High-throughput

0.445

High

556184

CADH1
Cadherin-1

1

12

Small-scale

0.445

High

1060363

SLC31
Amino acid transporter heavy chain SLC3A1

1

3

High-throughput

0.445

High

1280069

CTL1
Choline transporter-like protein 1

1

4

High-throughput

0.445

High

1280073

S1PR3
Sphingosine 1-phosphate receptor 3

1

6

High-throughput

0.445

High

1280066

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.438

High

218389

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.437

High

161143

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.426

High

292275

S22A3
Solute carrier family 22 member 3

1

0

High-throughput

0.426

High

1280067

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.426

High

1280083

CCG5
Voltage-dependent calcium channel gamma-5 subunit

1

1

High-throughput

0.407

High

1280093

PCDG5
Protocadherin gamma-A5

1

4

High-throughput

0.407

High

1058749

AMPE
Glutamyl aminopeptidase

2

0

High-throughput

0.328

High

239108

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.313

High

376616

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.279

Low

1124990

RCN2
Reticulocalbin-2

1

0

High-throughput

0.279

Low

1126315

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

1198717

MPPE1
Metallophosphoesterase 1

1

0

High-throughput

0.279

Low

1203706

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1280071

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1280072

OPALI
Opalin

1

0

High-throughput

0.279

Low

1280076

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.279

Low

1280079

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1280080

CP26B
Cytochrome P450 26B1

1

0

High-throughput

0.279

Low

1280075

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.232

Low

1280082

S52A1
Solute carrier family 52, riboflavin transporter, member 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025