HitPredict

Interactor 1: TIA1 (P52912)
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1)
Gene: TIA1

Interactor 2: PSPC1 (Q8R326)
Paraspeckle component 1 (Paraspeckle protein 1) (mPSP1)
Gene: PSPC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27160897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 386 Mm			1 523
+	Hs
		516608 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PSPC1_HUMAN (1-523): 1.06e-79: 260: 96.95
+	Mm
		665745 TIA1_MOUSE (1-386): 2.66e-116: 345: 100.00		PABP1_MOUSE (145-428): 1.42e-26: 115: 10.96
+	Mm
		857310 TIA1_MOUSE (1-386): 2.66e-116: 345: 100.00		ELAV1_MOUSE (83-155): 3.22e-13: 72.6: 29.11
+	Hs
		680465 TIA1_HUMAN (1-386): 2.53e-114: 340: 96.63		RAVR1_HUMAN (83-233): 3.45e-14: 77.2: 23.35
+	Hs
		680455 TIA1_HUMAN (1-386): 2.53e-114: 340: 96.63		ELAV1_HUMAN (83-155): 3.22e-13: 72.6: 29.11
+	Hs
		516495 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP4_HUMAN (4-444): 1.21e-49: 182: 12.76
+	Mm
		936687 Q80ZW7_MOUSE (1-386): 6.5e-111: 331: 95.88		ELAV1_MOUSE (83-155): 3.22e-13: 72.6: 29.11
+	Hs
		516339 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP1_HUMAN (145-428): 3.13e-26: 114: 10.96
+	Hs
		516689 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP3_HUMAN (145-428): 1.84e-24: 109: 9.59
+	Hs
		474021 PAB4L_HUMAN (103-303): 2.43e-39: 145: 22.93		PABP4_HUMAN (4-444): 1.21e-49: 182: 12.76
+	Hs
		516635 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		PABP5_HUMAN (4-157): 9.26e-23: 101: 18.24
+	Sc
		376694 PUB1_YEAST (7-185): 3.03e-31: 125: 40.56		PABP_YEAST (3-357): 5.64e-52: 187: 15.35
+	Hs
		516484 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		ELAV2_HUMAN (83-155): 1.32e-13: 74.1: 31.65
+	Hs
		516674 PABP1_HUMAN (3-303): 6.45e-67: 224: 24.68		RBM4_HUMAN (82-189): 4.98e-09: 60.1: 32.14
+	Hs
		516471 TIAR_HUMAN (98-295): 6.66e-36: 136: 24.02		PABP1_HUMAN (145-428): 3.13e-26: 114: 10.96
+	Hs
		474034 PAB4L_HUMAN (103-303): 2.43e-39: 145: 22.93		PABP5_HUMAN (4-157): 9.26e-23: 101: 18.24
+	Hs
		474019 PAB4L_HUMAN (103-303): 2.43e-39: 145: 22.93		ELAV2_HUMAN (83-155): 1.32e-13: 74.1: 31.65
+	Hs
		963526 TIAR_HUMAN (98-295): 6.66e-36: 136: 24.02		ELAV1_HUMAN (83-155): 3.22e-13: 72.6: 29.11