HitPredict

Interactor 1: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4

Interactor 2: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 16193069, 16704411, 28379137, 28714467, 17949747, 18272179, 18929572, 23913684, 24161953, 19278657
Identification Methods biochemical, two hybrid, x-ray crystallography, pull down, molecular sieving, light scattering, transmission electron microscopy
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Vps4_C, AAA_lid_3~AAA_lid_3, AAA_lid_3~Vps4_C, MIT~MIT, Vps4_C~Vps4_C
Common GO terms GO:0001778 - plasma membrane repair
GO:0005524 - ATP binding
GO:0005643 - nuclear pore
GO:0005737 - cytoplasm
GO:0005768 - endosome
and 27 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 437
Sc

1 437
+ Hs
+ Hs
+ At
+ Hs
+ Dm
+ Hs
+ Hs
+ Af
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024