HitPredict

Interactor 1: SEH1 (P53011)
Nucleoporin SEH1 (Nuclear pore protein SEH1) (SEC13 homolog 1)
Gene: SEH1

Interactor 2: NU116 (Q02630)
Nucleoporin NUP116/NSP116 (Nuclear pore protein NUP116/NSP116)
Gene: NUP116

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	12543930, 10684247, 29033133, 17418788
Identification Methods	affinity chromatography technology, biochemical, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006913 - nucleocytoplasmic transport GO:0017056 - structural constituent of nuclear pore GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 349 Sc			1 1113
+	Sc
		830669 SEH1_YEAST (1-349): 3.91e-85: 262: 100.00		NU145_YEAST (489-1108): 1.48e-68: 254: 23.15
+	Sc
		830680 SEC13_YEAST (1-346): 5.48e-68: 217: 21.51		NU145_YEAST (489-1108): 1.48e-68: 254: 23.15
+	Sp
		292982 SEC13_SCHPO (1-346): 1.74e-98: 295: 25.63		NU189_SCHPO (1-750): 8.91e-25: 114: 14.93
+	Hs
		858034 SEH1_HUMAN (2-347): 1.28e-76: 241: 32.87		NUP98_HUMAN (2-615): 2.83e-37: 155: 18.40
+	Sp
		1013470 SEH1_SCHPO (2-349): 2.04e-92: 281: 40.52		NU189_SCHPO (1-750): 8.91e-25: 114: 14.93
+	Hs
		857954 SEC13_HUMAN (1-349): 5.74e-69: 220: 24.45		NUP98_HUMAN (2-615): 2.83e-37: 155: 18.40
+	Sc
		858396 SEH1_YEAST (1-349): 3.91e-85: 262: 100.00		NU100_YEAST (1-708): 2.45e-22: 106: 16.36
+	Sc
		541905 SEH1_YEAST (1-349): 3.91e-85: 262: 100.00		NSP1_YEAST (371-960): 3.45e-17: 89.3: 12.84
+	Hs
		867085 SEC13_HUMAN (1-349): 5.74e-69: 220: 24.45		SC24C_HUMAN (158-472): 1.47e-27: 123: 11.60
+	Hs
		72755 SEH1_HUMAN (2-347): 1.28e-76: 241: 32.87		B4DET5_HUMAN (4-683): 7.76e-20: 97.7: 9.66
+	Sc
		822983 SEH1_YEAST (1-349): 3.91e-85: 262: 100.00		NUP57_YEAST (272-533): 3.69e-10: 65.9: 29.43
+	Sc
		774364 SEH1_YEAST (1-349): 3.91e-85: 262: 100.00		NU159_YEAST (4-454): 8.42e-09: 62.3: 10.53
+	Hs
		727302 SEH1_HUMAN (2-347): 1.28e-76: 241: 32.87		NU214_HUMAN (4-549): 7.13e-15: 82.3: 14.91
+	Sc
		971875 SEC13_YEAST (1-346): 5.48e-68: 217: 21.51		NU100_YEAST (1-708): 2.45e-22: 106: 16.36
+	Hs
		65045 SEH1_HUMAN (2-347): 1.28e-76: 241: 32.87		P121C_HUMAN (1-464): 1.28e-13: 77.7: 14.56
+	Hs
		834655 SEH1_HUMAN (2-347): 1.28e-76: 241: 32.87		NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56
+	Sc
		541924 SEC13_YEAST (1-346): 5.48e-68: 217: 21.51		NSP1_YEAST (371-960): 3.45e-17: 89.3: 12.84
+	Hs
		878229 SEC13_HUMAN (1-349): 5.74e-69: 220: 24.45		P121A_HUMAN (1-464): 2.06e-13: 77.3: 13.76
+	Sc
		823002 SEC13_YEAST (1-346): 5.48e-68: 217: 21.51		NUP57_YEAST (272-533): 3.69e-10: 65.9: 29.43
+	Sc
		774376 SEC13_YEAST (1-346): 5.48e-68: 217: 21.51		NU159_YEAST (4-454): 8.42e-09: 62.3: 10.53