Interactor 1: INO80 (P53115)
Chromatin-remodeling ATPase INO80 (EC 3.6.4.-) (Inositol-requiring protein 80)
Gene: INO80

Interactor 2: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 15045029, 10952318, 16429126, 26831523, 24034246, 12052880, 14645854, 15607974, 26656161, 27768892, 16554755, 14979041, 26798134, 26755556, 26306040, 28591576, 28272416, 30388237, 37968396, 17693258 and 1 others

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Identification Methods tandem affinity purification, affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~TIP49, SNF2-rel_dom~TIP49
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription
and 3 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1489
Sc

1 471
+ Sc
+ Dm
+ Sp
+ Sp
+ Dm
+ Sc
+ Sp
+ Sc
+ Sp
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Mm
+ Hs
+ Sc

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Last updated: 15 Jul 2024