Interactor 1: MLC1 (P53141)
Myosin light chain 1 (Calmodulin-like myosin light chain MLC1) (Myosin-2 light chain)
Gene: MLC1
Interactor 2: IQG1 (Q12280)
Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1)
Gene: IQG1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24413167, 15210731, 18675924, 37968396, 24895401, 11082046, 10873803, 12446742 |
| Identification Methods | affinity chromatography technology, protein complementation assay, pull down, two hybrid, anti tag coimmunoprecipitation, ubiquitin reconstruction, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~EF-hand_7, EF-hand_7~IQ |
| Common GO terms | GO:0000142 - cellular bud neck contractile ring GO:0005886 - plasma membrane GO:0005935 - cellular bud neck GO:0031991 - regulation of actomyosin contractile ring contraction GO:0032038 - myosin II heavy chain binding and 4 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
