HitPredict

Interactor 1: PESC (P53261)
Pescadillo homolog (Nucleolar protein 7) (Ribosomal RNA-processing protein 13)
Gene: NOP7

Interactor 2: MAK21 (Q12176)
Ribosome biogenesis protein MAK21 (Maintenance of killer protein 21) (Nucleolar complex protein 1)
Gene: MAK21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	11805826, 12374754, 18559667, 37811893, 38113283, 16429126, 35385737, 37968396, 23209026
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 605 Sc			1 1025
+	Hs
		132183 PESC_HUMAN (4-599): 0: 667: 37.40		NOC3L_HUMAN (79-790): 2.08e-151: 471: 15.71
+	Sc
		860892 PESC_YEAST (1-605): 0: 702: 100.00		NOC4_YEAST (306-801): 1.18e-103: 337: 15.98
+	Sc
		860895 PESC_YEAST (1-605): 0: 702: 100.00		NOC3_YEAST (124-769): 2.85e-92: 310: 13.15