HitPredict

Interactor 1: DAM1 (P53267)
DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1)
Gene: DAM1

Interactor 2: SPC19 (Q03954)
DASH complex subunit SPC19 (19 kDa spindle pole component protein) (Outer kinetochore protein SPC19)
Gene: SPC19

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.90	0.896

The method score is based on:

Property	Details
Experiments	11782438, 12925767, 34313341, 16554755, 17634282, 37968396
Identification Methods	affinity chromatography technology, pull down, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	DASH_Dam1~DASH_Spc19
Common GO terms	GO:0005737 - cytoplasm GO:0008608 - attachment of spindle microtubules to kinetochore GO:0031116 - positive regulation of microtubule polymerization GO:0042729 - DASH complex GO:0051301 - cell division and 4 others more... GO:0051987 - positive regulation of attachment of spindle microtubules to kinetochore GO:0072686 - mitotic spindle GO:1990758 - mitotic sister chromatid biorientation GO:1990976 - protein transport along microtubule to mitotic spindle pole body
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024