Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: ERC6L (Q2NKX8)
DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)
Gene: ERCC6L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.755

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 17218258, 25659891, 26291670, 35271311, 19596235, 20360068
Identification Methods affinity chromatography technology, far western blotting, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 603
Hs

1 1250
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024