HitPredict

Interactor 1: FOSB (P53539)
Protein FosB (FosB proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 3) (Transcription factor AP-1 subunit FosB)
Gene: FOSB

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15025563
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 338 Hs			1 2442
+	Hs
		548258 FOSL1_HUMAN (54-338): 8.08e-31: 119: 39.04		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		547833 ATF2_HUMAN (8-299): 1.6e-28: 117: 16.34		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		345507 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1081236 NF2L2_HUMAN (7-218): 1.08e-25: 109: 22.97		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		579220 ATF3_HUMAN (149-237): 5.19e-27: 106: 43.82		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Mm
		101443 NF2L2_MOUSE (7-218): 3.5e-28: 116: 21.97		F8VPR5_MOUSE (1-2442): 0: 1077: 95.67
+	Hs
		862616 FOSB_HUMAN (1-338): 5.83e-47: 163: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		548300 FOSL2_HUMAN (1-338): 9.55e-33: 125: 38.61		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		548240 FOSL1_HUMAN (54-338): 8.08e-31: 119: 39.04		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		547790 ATF2_HUMAN (8-299): 1.6e-28: 117: 16.34		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		345411 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998764 NF2L2_HUMAN (7-218): 1.08e-25: 109: 22.97		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70890 ATF2_MOUSE (8-302): 4.03e-26: 110: 16.03		EP300_MOUSE (1-2426): 0: 867: 53.61
+	Hs
		345579 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		170242 FOSL1_HUMAN (54-338): 8.08e-31: 119: 39.04		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		170197 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		170381 NF2L2_HUMAN (7-218): 1.08e-25: 109: 22.97		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		345480 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		345491 FOS_HUMAN (1-338): 8.95e-29: 116: 34.24		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		1017305 NF2L2_HUMAN (7-218): 1.08e-25: 109: 22.97		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09