HitPredict

Interactor 1: COPB (P53618)
Coatomer subunit beta (Beta-coat protein) (Beta-COP)
Gene: COPB1

Interactor 2: ARF5 (P84085)
ADP-ribosylation factor 5
Gene: ARF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	35844135, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 953 Hs			1 180
+	Hs
		863193 COPB_HUMAN (1-953): 0: 1109: 100.00		ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00
+	Hs
		574632 COPB_HUMAN (1-953): 0: 1109: 100.00		ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00
+	Hs
		863188 COPB_HUMAN (1-953): 0: 1109: 100.00		ARF3_HUMAN (1-180): 4.68e-67: 204: 78.89
+	Hs
		863200 COPB_HUMAN (1-953): 0: 1109: 100.00		ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56
+	Dm
		778361 COPB_DROME (3-951): 0: 1001: 67.08		ARF4_DROME (1-180): 1.02e-77: 231: 83.89
+	Dm
		799489 COPB_DROME (3-951): 0: 1001: 67.08		ARF1_DROME (1-179): 1.52e-66: 202: 79.89
+	Sc
		503102 COPB_YEAST (2-952): 0: 894: 42.32		ARF1_YEAST (1-179): 4.21e-78: 232: 69.83
+	Dm
		778364 Q24253_DROME (17-529): 9.6e-139: 439: 16.08		ARF4_DROME (1-180): 1.02e-77: 231: 83.89
+	Hs
		912839 AP2B1_HUMAN (19-529): 1.43e-140: 444: 15.41		ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00
+	Hs
		912875 AP1B1_HUMAN (17-529): 2.58e-139: 442: 15.73		ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00
+	Hs
		950481 AP1B1_HUMAN (17-529): 2.58e-139: 442: 15.73		ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56
+	Dm
		897433 Q24253_DROME (17-529): 9.6e-139: 439: 16.08		ARF1_DROME (1-179): 1.52e-66: 202: 79.89
+	Hs
		119946 AP3B1_HUMAN (16-548): 8.87e-121: 396: 17.71		ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00
+	Zm
		30041 A0A1D6K3D9_MAIZE (49-554): 2.61e-128: 410: 16.13		B4FB55_MAIZE (8-180): 6.02e-66: 202: 17.42
+	Hs
		212615 AP1G1_HUMAN (21-496): 7.77e-121: 389: 14.29		ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00
+	Hs
		119950 AP3B1_HUMAN (16-548): 8.87e-121: 396: 17.71		ARF5_HUMAN (1-180): 1.69e-69: 210: 100.00
+	Hs
		119943 AP3B1_HUMAN (16-548): 8.87e-121: 396: 17.71		ARF3_HUMAN (1-180): 4.68e-67: 204: 78.89
+	Hs
		119949 AP3B1_HUMAN (16-548): 8.87e-121: 396: 17.71		ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56
+	Bt
		950590 AP3B1_BOVIN (16-522): 1.3e-118: 390: 18.18		ARF1_BOVIN (1-180): 3.45e-67: 204: 80.56
+	Hs
		212618 AP1G1_HUMAN (21-496): 7.77e-121: 389: 14.29		ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56