HitPredict

Interactor 1: COPA (P53621)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA

Interactor 2: SCYL1 (Q96KG9)
N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase)
Gene: SCYL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	30631079, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0016020 - membrane GO:0030126 - COPI vesicle coat
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1224 Hs			1 808
+	Hs
		863481 COPA_HUMAN (1-1224): 0: 1334: 100.00		PACE1_HUMAN (9-436): 4.41e-112: 360: 27.31
+	Hs
		863389 COPA_HUMAN (1-1224): 0: 1334: 100.00		HUNK_HUMAN (6-301): 1.19e-20: 99.2: 20.98
+	Hs
		725525 COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53		SCYL1_HUMAN (1-808): 0: 621: 100.00
+	Hs
		725489 COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53		PACE1_HUMAN (9-436): 4.41e-112: 360: 27.31