Protein: STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Oligosaccharyl transferase subunit STT3) (EC 2.4.99.18) (Staurosporine and temperature sensitivity protein 3)

Gene: STT3
Organism: Saccharomyces cerevisiae S288C
Interactions: 58
UniProt ID: P39007

Gene Ontology (top 5):
GO:0004579 - dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0008250 - oligosaccharyltransferase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

754622

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

11

2

Small-scale

0.971

High

809019

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

10

2

Small-scale

0.968

High

809023

OST3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

7

5

Small-scale

0.954

High

809039

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4

9

0

Small-scale

0.918

High

809031

OST6
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6

4

5

Small-scale

0.887

High

809020

OST2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2

4

2

Small-scale

0.875

High

809038

OST5
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5

3

0

Small-scale

0.787

High

809013

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

2

1

Small-scale

0.754

High

809030

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

6

0

Small-scale

0.686

High

748394

SC61A
Protein transport protein SEC61

2

2

Small-scale

0.628

High

809025

SC6B1
Protein transport protein SBH1

2

1

Small-scale

0.619

High

754686

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

2

3

Small-scale

0.584

High

523958

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.521

High

793128

YRO2
Protein YRO2

1

0

High-throughput

0.518

High

809026

SC6B2
Protein transport protein SBH2

1

1

Small-scale

0.481

High

577130

SEC63
Protein translocation protein SEC63

1

6

High-throughput

0.479

High

679681

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

726085

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

3

High-throughput

0.479

High

747679

MNS1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

4

High-throughput

0.479

High

809015

SSO2
Protein SSO2

1

2

High-throughput

0.479

High

809016

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

2

Small-scale

0.479

High

809017

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.479

High

809021

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

3

High-throughput

0.479

High

809035

PMT7
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

1

3

High-throughput

0.479

High

809036

YET3
Endoplasmic reticulum transmembrane protein 3

1

1

High-throughput

0.479

High

809027

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.460

High

438693

SC160
Protein SCP160

1

0

High-throughput

0.458

High

554346

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.458

High

678007

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

754396

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

780747

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

782204

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

High-throughput

0.458

High

796929

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

802480

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.458

High

809018

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.458

High

809029

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

809033

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

809034

SPC2
Signal peptidase complex subunit 2

1

0

High-throughput

0.458

High

809037

SPC3
Signal peptidase complex subunit 3

1

0

High-throughput

0.458

High

392731

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.437

High

526703

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.437

High

579398

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.437

High

727027

HS104
Heat shock protein 104

1

1

High-throughput

0.437

High

752261

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.437

High

794988

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

544883

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

665820

KPC1
Protein kinase C-like 1

1

0

Small-scale

0.288

High

701701

URA7
CTP synthase 1

1

0

High-throughput

0.269

Low

444515

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.249

Low

707103

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709753

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

758444

YKK0
Probable intramembrane protease YKL100C

1

0

High-throughput

0.249

Low

809014

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

809022

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

809024

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

809028

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

809032

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025