HitPredict

Interactor 1: LIMK2 (P53671)
LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)
Gene: LIMK2

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17053785
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 638 Hs			1 1356
+	Hs
		665414 EPHA3_HUMAN (7-629): 2.44e-151: 463: 18.27		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872679 EPHA4_HUMAN (7-631): 3.48e-149: 458: 18.13		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		1072560 EPHA7_HUMAN (7-632): 9.5e-148: 454: 17.39		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872464 EPHA5_HUMAN (7-613): 3.7e-142: 441: 17.18		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		665294 EPHA2_HUMAN (9-636): 4.26e-137: 426: 18.52		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872669 EPHA4_HUMAN (7-631): 3.48e-149: 458: 18.13		MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66
+	Hs
		1072546 EPHA7_HUMAN (7-632): 9.5e-148: 454: 17.39		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Hs
		665393 EPHA3_HUMAN (7-629): 2.44e-151: 463: 18.27		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		665589 EPHB2_HUMAN (5-635): 1.78e-149: 461: 16.84		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872638 EPHA4_HUMAN (7-631): 3.48e-149: 458: 18.13		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1020163 EPHA7_HUMAN (7-632): 9.5e-148: 454: 17.39		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		665633 EPHB2_HUMAN (5-635): 1.78e-149: 461: 16.84		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		872678 EPHA4_HUMAN (7-631): 3.48e-149: 458: 18.13		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		1072558 EPHA7_HUMAN (7-632): 9.5e-148: 454: 17.39		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		872431 EPHA5_HUMAN (7-613): 3.7e-142: 441: 17.18		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		665600 EPHB2_HUMAN (5-635): 1.78e-149: 461: 16.84		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		1049958 EPHA7_HUMAN (7-632): 9.5e-148: 454: 17.39		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		872410 EPHB3_HUMAN (12-634): 5.46e-141: 437: 17.11		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		665228 EPHA2_HUMAN (9-636): 4.26e-137: 426: 18.52		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		600564 EPHA1_HUMAN (5-636): 6.05e-133: 416: 19.06		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50