Protein: ATG27
Autophagy-related protein 27 (Enhancer of VPS34 missorting protein 1)

Gene: ATG27
Organism: Saccharomyces cerevisiae S288C
Interactions: 96
UniProt ID: P46989

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000139 - Golgi membrane
GO:0000324 - fungal-type vacuole
GO:0000407 - phagophore assembly site
GO:0000425 - pexophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

863836

ATG9
Autophagy-related protein 9

9

0

Small-scale

0.720

High

733812

VPS10
Vacuolar protein sorting/targeting protein VPS10

2

1

High-throughput

0.614

High

863831

ATG23
Autophagy-related protein 23

2

0

Small-scale

0.593

High

794787

SFT2
Protein transport protein SFT2

2

0

High-throughput

0.588

High

809120

AKR1
Palmitoyltransferase AKR1

2

0

High-throughput

0.588

High

849641

EMP47
Protein EMP47

2

0

High-throughput

0.588

High

863813

ATG27
Autophagy-related protein 27

2

0

High-throughput

0.588

High

863838

RBD2
Rhomboid-type serine protease 2

2

0

High-throughput

0.587

High

863832

TLG2
t-SNARE affecting a late Golgi compartment protein 2

2

1

Small-scale

0.571

High

579640

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.559

High

863833

SNX3
Sorting nexin-3

1

2

High-throughput

0.541

High

863841

VPS5
Vacuolar protein sorting-associated protein 5

1

1

High-throughput

0.541

High

745215

COT1
Vacuolar zinc transporter COT1

1

0

High-throughput

0.518

High

748264

VPS17
Vacuolar protein sorting-associated protein 17

1

0

High-throughput

0.518

High

863825

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.518

High

863829

FMP42
Protein FMP42

1

0

High-throughput

0.518

High

863834

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.518

High

807730

ATC2
Calcium-transporting ATPase 2

1

1

High-throughput

0.494

High

863817

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.486

High

458582

SEC4
Ras-related protein SEC4

1

1

High-throughput

0.479

High

527030

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.479

High

744390

ATC5
Phospholipid-transporting ATPase DNF1

1

1

High-throughput

0.479

High

745362

EMP24
Endosomal protein P24B

1

1

High-throughput

0.479

High

746139

PEP12
Syntaxin PEP12

1

1

High-throughput

0.479

High

748754

YPT7
Ypt/Rab-type GTPase YPT7

1

1

High-throughput

0.479

High

779616

VPS21
Vacuolar protein sorting-associated protein 21

1

2

High-throughput

0.479

High

803088

GOSR1
Golgi SNAP receptor complex member 1

1

2

High-throughput

0.479

High

824612

VTH1
VPS10 homolog 1

1

1

High-throughput

0.479

High

825927

ATC7
Phospholipid-transporting ATPase NEO1

1

1

High-throughput

0.479

High

863814

SNX4
Sorting nexin-4

1

1

Small-scale

0.479

High

863818

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

863820

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.479

High

863830

ERP1
Protein ERP1

1

2

High-throughput

0.479

High

863837

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.479

High

806307

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

359275

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.458

High

368000

ENO2
Enolase 2

1

0

High-throughput

0.458

High

376316

YPT1
GTP-binding protein YPT1

1

0

High-throughput

0.458

High

394682

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.458

High

448550

RHO1
GTP-binding protein RHO1

1

0

High-throughput

0.458

High

564747

ATC1
Calcium-transporting ATPase 1

1

0

High-throughput

0.458

High

582486

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.458

High

639035

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.458

High

646256

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.458

High

652932

BET1
Protein transport protein BET1

1

0

High-throughput

0.458

High

656524

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.458

High

673643

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.458

High

679823

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

732168

COPG
Coatomer subunit gamma

1

0

High-throughput

0.458

High

746446

SSO1
Protein SSO1

1

0

High-throughput

0.458

High

751591

SNC2
Synaptobrevin homolog 2

1

0

High-throughput

0.458

High

752435

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

758109

CASP
Protein CASP

1

0

High-throughput

0.458

High

782619

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.458

High

790330

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.458

High

795428

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

800380

YPT31
GTP-binding protein YPT31/YPT8

1

0

High-throughput

0.458

High

801070

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.458

High

806238

SVP26
Protein SVP26

1

0

High-throughput

0.458

High

813908

ERV46
ER-derived vesicles protein ERV46

1

0

High-throughput

0.458

High

815095

SS120
Protein SSP120

1

0

High-throughput

0.458

High

851249

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.458

High

863816

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

863819

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.458

High

863826

VTI1
t-SNARE VTI1

1

0

High-throughput

0.458

High

863827

SEC13
Protein transport protein SEC13

1

0

High-throughput

0.458

High

863839

YOP1
Protein YOP1

1

0

High-throughput

0.458

High

863822

SED5
Integral membrane protein SED5

1

2

Small-scale

0.445

High

536141

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.438

High

863840

COX26
Cytochrome c oxidase subunit 26, mitochondrial

1

0

High-throughput

0.438

High

524379

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.437

High

741856

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.437

High

779655

YPT52
GTP-binding protein YPT52

1

1

High-throughput

0.437

High

781009

VPS24
Vacuolar protein-sorting-associated protein 24

1

2

High-throughput

0.437

High

781325

DID4
DOA4-independent degradation protein 4

1

2

High-throughput

0.437

High

815027

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.437

High

863821

DID2
Vacuolar protein-sorting-associated protein 46

1

2

High-throughput

0.437

High

797850

FTH1
Iron transporter FTH1

2

0

High-throughput

0.320

High

806226

CTR2
Copper transport protein CTR2

1

0

High-throughput

0.282

High

863823

VPS16
Vacuolar protein sorting-associated protein 16

1

0

High-throughput

0.282

High

863824

YMB8
Uncharacterized vacuolar membrane protein YML018C

1

0

High-throughput

0.282

High

863835

TMS1
Membrane protein TMS1

1

0

High-throughput

0.282

High

863828

VBA4
Vacuolar basic amino acid transporter 4

1

0

High-throughput

0.251

Low

365095

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

444558

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.249

Low

545370

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.249

Low

553924

WHI2
Growth regulation protein

1

0

High-throughput

0.249

Low

623885

MYO2
Myosin-2

1

0

High-throughput

0.249

Low

672819

ELO2
Fatty acid elongase 2

1

0

High-throughput

0.249

Low

705195

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

707486

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

743469

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.249

Low

747448

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

817892

IMB4
Importin subunit beta-4

1

0

High-throughput

0.249

Low

863815

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025