HitPredict

Interactor 1: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Interactor 2: PAK5 (Q9P286)
Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)
Gene: PAK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 719
+	Hs
		1315718 AP1M1_HUMAN (2-137): 4.68e-44: 150: 14.71		PAK5_HUMAN (1-719): 0: 673: 100.00
+	Hs
		1071674 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		KS6A2_HUMAN (447-714): 4.31e-113: 359: 24.30
+	Hs
		850696 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		KS6A3_HUMAN (386-714): 3.35e-112: 357: 22.41
+	Hs
		1073464 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		KS6A1_HUMAN (386-714): 2.98e-109: 349: 22.03
+	Sc
		959832 AP2S_YEAST (2-142): 1.37e-45: 146: 48.97		SKM1_YEAST (444-706): 3.7e-64: 227: 39.18