HitPredict

Interactor 1: SNO2 (P53823)
Probable pyridoxal 5'-phosphate synthase subunit SNO2 (EC 4.3.3.6) (PDX2 homolog 2) (Pdx2.2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)
Gene: SNO2

Interactor 2: SNZ2 (P53824)
Probable pyridoxal 5'-phosphate synthase subunit SNZ2 (PLP synthase subunit SNZ2) (EC 4.3.3.6) (PDX1 homolog 2) (Pdx1.2)
Gene: SNZ2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.850

Property	Details
Experiments	11283351, 10655498, 18719252
Identification Methods	two hybrid pooling approach, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SNO~SOR_SNZ
Common GO terms	GO:0036381 - pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity GO:0042823 - pyridoxal phosphate biosynthetic process
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 222 Sc			1 298
+	Sc
		796972 SNO3_YEAST (1-222): 6.46e-121: 344: 99.10		SNZ3_YEAST (1-298): 5.47e-175: 487: 99.66
+	Sc
		796973 SNO3_YEAST (1-222): 6.46e-121: 344: 99.10		SNZ2_YEAST (1-298): 5.18e-175: 487: 100.00
+	Sc
		796978 SNO2_YEAST (1-222): 3.94e-121: 344: 100.00		SNZ3_YEAST (1-298): 5.47e-175: 487: 99.66
+	Sc
		796976 SNO3_YEAST (1-222): 6.46e-121: 344: 99.10		SNZ1_YEAST (3-298): 8.55e-162: 453: 80.41
+	Sc
		865168 SNO2_YEAST (1-222): 3.94e-121: 344: 100.00		SNZ1_YEAST (3-298): 8.55e-162: 453: 80.41
+	Sc
		796982 SNO1_YEAST (4-216): 1.54e-103: 300: 66.67		SNZ3_YEAST (1-298): 5.47e-175: 487: 99.66
+	Sc
		865170 SNO1_YEAST (4-216): 1.54e-103: 300: 66.67		SNZ2_YEAST (1-298): 5.18e-175: 487: 100.00
+	Sc
		975162 SNO1_YEAST (4-216): 1.54e-103: 300: 66.67		SNZ1_YEAST (3-298): 8.55e-162: 453: 80.41
+	At
		1226677 PDX2_ARATH (3-213): 4.83e-76: 231: 31.44		PDX13_ARATH (2-281): 6.44e-166: 464: 65.00
+	At
		285347 PDX2_ARATH (3-213): 4.83e-76: 231: 31.44		PDX11_ARATH (2-291): 1.89e-161: 453: 62.41
+	Pf
		86932 PDX2_PLAF7 (3-220): 7.26e-78: 235: 34.93		PDX1_PLAF7 (6-276): 9.5e-149: 420: 59.04
+	Sp
		144183 YFM8_SCHPO (5-217): 1.07e-67: 209: 39.19		PDX1_SCHPO (5-298): 7.3e-157: 441: 65.65
+	Bs
		741664 PDXT_BACSU (3-213): 3.73e-66: 204: 34.60		PDXS_BACSU (5-298): 8.96e-150: 423: 58.50
+	Ph
		223429 PDXT_PYRHO (3-216): 1.25e-72: 220: 35.05		PDXS_PYRHO (5-297): 6.79e-142: 404: 50.30