HitPredict

Interactor 1: SC24C (P53992)
Protein transport protein Sec24C (SEC24-related protein C)
Gene: SEC24C

Interactor 2: SC23A (Q15436)
Protein transport protein Sec23A (hSec23A) (SEC23-related protein A)
Gene: SEC23A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.913

The method score is based on:

Property Details
Experiments 10075675, 35271311, 33961781, 18692470
Identification Methods affinity chromatography technology, two hybrid, cosedimentation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gelsolin~Gelsolin, Gelsolin~Sec23_helical, Gelsolin~Sec23_trunk, Sec23_BS~Sec23_helical, Sec23_BS~Sec23_trunk, Sec23_BS~zf-Sec23_Sec24, Sec23_helical~Sec23_trunk, Sec23_trunk~Sec23_trunk, zf-Sec23_Sec24~zf-Sec23_Sec24
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0008270 - zinc ion binding
GO:0012507 - ER to Golgi transport vesicle membrane
and 3 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1094
Hs

1 765
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+ Sp
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+ Sp
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+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024