Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 11278509, 29523790, 17984114, 12606585, 19956565, 15064730, 11309417, 19671661, 18562274
Identification Methods affinity chromatography technology, two hybrid, pull down, far western blotting, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000228 - nuclear chromosome
GO:0000724 - double-strand break repair via homologous recombination
GO:0000800 - lateral element
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
and 17 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1417
Hs

1 339
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024