Interactor 1: SYRC (P54136)
Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)
Gene: RARS1

Interactor 2: AIMP1 (Q12904)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]
Gene: AIMP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.732

The method score is based on:

Property Details
Experiments 10358004, 28514442, 32296183, 33961781, 17443684, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000049 - tRNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 660
Hs

1 312
+ Dm
+ Ce
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024