HitPredict

Interactor 1: HIRA (P54198)
Protein HIRA (TUP1-like enhancer of split protein 1)
Gene: HIRA

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21724829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1017 Hs			1 136
+	Hs
		867850 HIRA_HUMAN (1-1017): 0: 779: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		867853 HIRA_HUMAN (1-1017): 0: 779: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		952748 HIRA_MOUSE (1-1017): 0: 751: 95.67		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		828179 HIRA_HUMAN (1-1017): 0: 779: 100.00		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	At
		886471 HIRA_ARATH (173-1016): 2.81e-111: 370: 17.12		H33_ARATH (1-136): 4.35e-62: 188: 96.32
+	Hs
		934716 CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1024551 CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1024562 CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		952307 CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Sc
		690852 HIR1_YEAST (1-856): 9.68e-89: 304: 19.19		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		902046 CAC2_YEAST (1-423): 7.16e-88: 292: 20.29		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		730914 CAC2_YEAST (1-423): 7.16e-88: 292: 20.29		CENPA_YEAST (18-134): 1.58e-41: 139: 56.67
+	Hs
		935208 TBL1R_HUMAN (159-398): 4.63e-34: 140: 13.84		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		245614 TBL1X_HUMAN (168-360): 7.84e-23: 106: 18.67		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		903117 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		903260 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		903128 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Sc
		690885 HIR2_YEAST (1-535): 8.64e-20: 97.6: 16.67		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Hs
		934971 DAW1_HUMAN (406-799): 2.99e-13: 74.9: 8.06		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Sc
		690871 HIR2_YEAST (1-535): 8.64e-20: 97.6: 16.67		CENPA_YEAST (18-134): 1.58e-41: 139: 56.67