Interactor 1: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Interactor 2: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 35741099, 16194547, 21780213, 22129356, 16525503
Identification Methods pull down, filter binding, fluorescence technology, mass spectrometry studies of complexes, competition binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Josephin~Josephin, UIM~UIM
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 32 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 361
Hs

1 361
+ Mm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024