HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: RFOX1 (Q9NWB1)
RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A) (Hexaribonucleotide-binding protein 1)
Gene: RBFOX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007399 - nervous system development
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 397
+	Hs
		198864 ATX1_HUMAN (1-815): 0: 1349: 100.00		RFOX2_HUMAN (8-397): 5.93e-40: 148: 61.28
+	Hs
		868508 ATX1_HUMAN (1-815): 0: 1349: 100.00		ELAV1_HUMAN (33-250): 6.98e-22: 97.3: 15.18
+	Hs
		868484 ATX1_HUMAN (1-815): 0: 1349: 100.00		CIRBP_HUMAN (114-200): 2.91e-16: 78: 33.71
+	Mm
		869139 ATX1_MOUSE (1-815): 0: 1271: 86.89		RBM39_MOUSE (84-201): 1.14e-26: 113: 28.33
+	Mm
		868896 ATX1_MOUSE (1-815): 0: 1271: 86.89		ELAV1_MOUSE (33-250): 1.27e-21: 96.6: 15.18
+	Hs
		473570 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		RFOX1_HUMAN (1-397): 7.32e-79: 250: 100.00
+	Hs
		198833 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		RFOX2_HUMAN (8-397): 5.93e-40: 148: 61.28