Protein: LEG7
Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced gene 1 protein)

Gene: LEG7, LGALS7
Organism: Homo sapiens
Interactions: 211
UniProt ID: P47929

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

868658

LEG7
Galectin-7

2

17

Small-scale

0.768

High

868768

RBM24
RNA-binding protein 24

3

8

High-throughput

0.667

High

371436

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.633

High

600539

ZSC20
Zinc finger and SCAN domain-containing protein 20

2

1

High-throughput

0.628

High

868701

PKN2
Serine/threonine-protein kinase N2

3

0

High-throughput

0.622

High

565090

CSPG2
Versican core protein

1

14

High-throughput

0.618

High

868680

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

2

3

High-throughput

0.611

High

868683

GAB1
GRB2-associated-binding protein 1

2

1

High-throughput

0.611

High

868702

DPYL2
Dihydropyrimidinase-related protein 2

2

3

High-throughput

0.611

High

868705

TBB8
Tubulin beta-8 chain

2

2

High-throughput

0.611

High

868711

MYOME
Myomegalin

2

10

High-throughput

0.611

High

868740

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

2

1

High-throughput

0.611

High

868769

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

2

3

High-throughput

0.611

High

868795

DD19B
ATP-dependent RNA helicase DDX19B

2

6

High-throughput

0.611

High

220078

TGM5
Protein-glutamine gamma-glutamyltransferase 5

2

1

High-throughput

0.606

High

600765

HSP76
Heat shock 70 kDa protein 6

2

5

High-throughput

0.606

High

282685

E2F6
Transcription factor E2F6

2

0

High-throughput

0.602

High

720089

PURA2
Adenylosuccinate synthetase isozyme 2

2

0

High-throughput

0.585

High

849437

NAMPT
Nicotinamide phosphoribosyltransferase

2

0

High-throughput

0.585

High

868760

INT14
Integrator complex subunit 14

2

0

High-throughput

0.585

High

868781

MKS1
Tectonic-like complex member MKS1

2

0

High-throughput

0.585

High

868784

KLHL8
Kelch-like protein 8

2

0

High-throughput

0.585

High

868675

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

0

High-throughput

0.580

High

868698

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

2

0

High-throughput

0.580

High

868731

YAF2
YY1-associated factor 2

2

0

High-throughput

0.580

High

868800

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

0

High-throughput

0.580

High

868776

TB22B
TBC1 domain family member 22B

2

2

High-throughput

0.574

High

868799

FCF1
rRNA-processing protein FCF1 homolog

2

2

High-throughput

0.574

High

868741

DOCK8
Dedicator of cytokinesis protein 8

2

1

High-throughput

0.571

High

155838

DPYL4
Dihydropyrimidinase-related protein 4

2

3

High-throughput

0.558

High

868690

DPOA2
DNA polymerase alpha subunit B

2

1

High-throughput

0.558

High

868722

VP13B
Intermembrane lipid transfer protein VPS13B

2

2

High-throughput

0.558

High

868763

DPYL5
Dihydropyrimidinase-related protein 5

2

3

High-throughput

0.558

High

868779

PAPD1
Poly(A) RNA polymerase, mitochondrial

2

1

High-throughput

0.558

High

269841

IGSF3
Immunoglobulin superfamily member 3

1

12

High-throughput

0.553

High

132577

UPK1A
Uroplakin-1a

1

11

High-throughput

0.536

High

161699

APAF
Apoptotic protease-activating factor 1

1

6

High-throughput

0.536

High

292581

RENR
Renin receptor

1

1

High-throughput

0.536

High

395669

ESR1
Estrogen receptor

1

7

High-throughput

0.536

High

420247

IFNA4
Interferon alpha-4

1

1

High-throughput

0.536

High

552161

ADT3
ADP/ATP translocase 3

1

6

High-throughput

0.536

High

602760

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

622775

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

4

High-throughput

0.536

High

733303

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

868669

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.536

High

868670

SSBP2
Single-stranded DNA-binding protein 2

1

3

High-throughput

0.536

High

868685

TBB3
Tubulin beta-3 chain

1

2

High-throughput

0.536

High

868697

RHEB
GTP-binding protein Rheb

1

7

High-throughput

0.536

High

868710

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

4

High-throughput

0.536

High

868717

OPN5
Opsin-5

1

4

High-throughput

0.536

High

868723

PCGF5
Polycomb group RING finger protein 5

1

16

High-throughput

0.536

High

868728

ZC3C1
Zinc finger C3HC-type protein 1

1

1

High-throughput

0.536

High

868739

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

1

5

High-throughput

0.536

High

868759

CDK15
Cyclin-dependent kinase 15

1

2

High-throughput

0.536

High

868778

KLH11
Kelch-like protein 11

1

1

High-throughput

0.536

High

868789

PHF11
PHD finger protein 11

1

1

High-throughput

0.536

High

868798

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.536

High

868801

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

High-throughput

0.536

High

868699

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.515

High

868756

DDT4L
DNA damage-inducible transcript 4-like protein

1

2

High-throughput

0.515

High

317146

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.513

High

666809

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

845227

GDF5
Growth/differentiation factor 5

1

0

High-throughput

0.513

High

868665

DSCR6
Protein ripply3

1

0

High-throughput

0.513

High

868672

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

868681

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.513

High

868686

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

868715

JADE1
Protein Jade-1

1

0

High-throughput

0.513

High

868725

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.513

High

868743

METL6
tRNA N(3)-cytidine methyltransferase METTL6

1

0

High-throughput

0.513

High

868745

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

868753

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

868764

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.513

High

868766

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.513

High

868775

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

868777

SETD4
SET domain-containing protein 4

1

0

High-throughput

0.513

High

868786

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.513

High

868788

SMBT1
Scm-like with four MBT domains protein 1

1

0

High-throughput

0.513

High

868791

PRDM4
PR domain zinc finger protein 4

1

0

High-throughput

0.513

High

868792

PALD
Paladin

1

0

High-throughput

0.513

High

868803

RN115
E3 ubiquitin-protein ligase RNF115

1

0

High-throughput

0.513

High

868666

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.501

High

64857

RCCD1
RCC1 domain-containing protein 1

1

3

High-throughput

0.489

High

229221

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

4

High-throughput

0.489

High

254879

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.489

High

868660

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

868664

STX17
Syntaxin-17

1

2

High-throughput

0.489

High

868674

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

7

High-throughput

0.489

High

868706

FNDC1
Fibronectin type III domain-containing protein 1

1

15

High-throughput

0.489

High

868719

AEBP2
Zinc finger protein AEBP2

1

1

High-throughput

0.489

High

868738

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.489

High

868748

ZDH19
Palmitoyltransferase ZDHHC19

1

3

High-throughput

0.489

High

868752

PIGT
GPI-anchor transamidase component PIGT

1

1

High-throughput

0.489

High

868758

DOCK7
Dedicator of cytokinesis protein 7

1

1

High-throughput

0.489

High

141909

PODXL
Podocalyxin

1

6

High-throughput

0.479

High

172564

XPO1
Exportin-1

1

4

High-throughput

0.479

High

302426

RNF8
E3 ubiquitin-protein ligase RNF8

1

13

High-throughput

0.479

High

374458

RASH
GTPase HRas

1

10

High-throughput

0.479

High

389144

FINC
Fibronectin

1

20

High-throughput

0.479

High

415423

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.479

High

424159

S10A8
Protein S100-A8

1

4

High-throughput

0.479

High

444931

S10A9
Protein S100-A9

1

4

High-throughput

0.479

High

456205

CATD
Cathepsin D

1

1

High-throughput

0.479

High

456653

ANXA2
Annexin A2

1

8

High-throughput

0.479

High

457846

INVO
Involucrin

1

1

High-throughput

0.479

High

462851

LAMB1
Laminin subunit beta-1

1

20

High-throughput

0.479

High

484987

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

8

High-throughput

0.479

High

577664

PLAK
Junction plakoglobin

1

5

High-throughput

0.479

High

587427

TFE2
Transcription factor E2-alpha

1

2

High-throughput

0.479

High

587587

DESP
Desmoplakin

1

4

High-throughput

0.479

High

590835

TIMP2
Metalloproteinase inhibitor 2

1

1

High-throughput

0.479

High

606405

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

623181

RO52
E3 ubiquitin-protein ligase TRIM21

1

14

High-throughput

0.479

High

655738

TBG1
Tubulin gamma-1 chain

1

5

High-throughput

0.479

High

673759

LAMA1
Laminin subunit alpha-1

1

18

High-throughput

0.479

High

713341

SPB3
Serpin B3

1

5

High-throughput

0.479

High

713944

PML
Protein PML

1

11

High-throughput

0.479

High

730444

1433S
14-3-3 protein sigma

1

8

High-throughput

0.479

High

787619

SPB5
Serpin B5

1

7

High-throughput

0.479

High

789429

PPARG
Peroxisome proliferator-activated receptor gamma

1

9

Small-scale

0.479

High

868659

SPB4
Serpin B4

1

5

High-throughput

0.479

High

868661

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

868662

HIRA
Protein HIRA

1

4

Small-scale

0.479

High

868667

ACTA
Actin, aortic smooth muscle

1

6

High-throughput

0.479

High

868668

TBA1B
Tubulin alpha-1B chain

1

4

High-throughput

0.479

High

868671

PKD1
Polycystin-1

1

7

High-throughput

0.479

High

868673

FABP5
Fatty acid-binding protein 5

1

3

High-throughput

0.479

High

868676

APLP2
Amyloid beta precursor like protein 2

1

5

High-throughput

0.479

High

868677

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.479

High

868678

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

868679

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.479

High

868682

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

868684

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

868687

DX39B
Spliceosome RNA helicase DDX39B

1

4

High-throughput

0.479

High

868688

NID2
Nidogen-2

1

11

High-throughput

0.479

High

868691

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

19

High-throughput

0.479

High

868692

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

868700

LAMA4
Laminin subunit alpha-4

1

19

High-throughput

0.479

High

868703

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

868708

DCAF6
DDB1- and CUL4-associated factor 6

1

6

High-throughput

0.479

High

868709

COL12
Collectin-12

1

10

High-throughput

0.479

High

868716

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

868718

CSPG4
Chondroitin sulfate proteoglycan 4

1

15

High-throughput

0.479

High

868720

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.479

High

868750

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.479

High

868751

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

868770

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

868783

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.479

High

868785

HECW2
E3 ubiquitin-protein ligase HECW2

1

3

High-throughput

0.479

High

868787

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

868790

LCAP
Leucyl-cystinyl aminopeptidase

1

5

High-throughput

0.479

High

868794

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.479

High

868796

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.479

High

868797

FBW1A
F-box/WD repeat-containing protein 1A

1

4

High-throughput

0.479

High

868802

LOXL2
Lysyl oxidase homolog 2

1

5

High-throughput

0.479

High

293357

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

331975

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.458

High

667631

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

692668

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.458

High

868693

CRYM
Ketimine reductase mu-crystallin

1

0

High-throughput

0.458

High

868694

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

868734

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

868761

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.458

High

213398

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

1

High-throughput

0.445

High

463019

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.445

High

703490

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.445

High

868689

DAG1
Dystroglycan 1

1

5

Small-scale

0.445

High

868724

NEK8
Serine/threonine-protein kinase Nek8

1

2

High-throughput

0.445

High

868730

TEX14
Inactive serine/threonine-protein kinase TEX14

1

5

High-throughput

0.445

High

868737

POC5
Centrosomal protein POC5

1

2

Small-scale

0.445

High

868772

CLK4
Dual specificity protein kinase CLK4

1

2

High-throughput

0.445

High

868695

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.437

High

868696

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

20

High-throughput

0.437

High

868707

SDK2
Protein sidekick-2

1

13

High-throughput

0.437

High

868714

SCAR3
Scavenger receptor class A member 3

1

8

High-throughput

0.437

High

868721

SDK1
Protein sidekick-1

1

12

High-throughput

0.437

High

868732

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.437

High

868735

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

1

High-throughput

0.437

High

868736

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.437

High

868746

TP4AP
Short transient receptor potential channel 4-associated protein

1

1

High-throughput

0.437

High

868747

POF1B
Protein POF1B

1

1

High-throughput

0.437

High

868749

RND1
Rho-related GTP-binding protein Rho6

1

6

High-throughput

0.437

High

868755

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.437

High

868773

K1549
UPF0606 protein KIAA1549

1

7

High-throughput

0.437

High

868774

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.437

High

868793

HEG1
Protein HEG homolog 1

1

18

High-throughput

0.437

High

868805

S12A7
Solute carrier family 12 member 7

1

20

High-throughput

0.437

High

690078

AVR2A
Activin receptor type-2A

1

0

High-throughput

0.426

High

868712

RNLS
Renalase

1

0

Small-scale

0.426

High

868726

PIM3
Serine/threonine-protein kinase pim-3

1

0

High-throughput

0.426

High

868780

IRAK4
Interleukin-1 receptor-associated kinase 4

1

0

High-throughput

0.426

High

220528

CAH12
Carbonic anhydrase 12

1

7

High-throughput

0.417

High

868713

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.407

High

868771

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.407

High

868663

DPOE2
DNA polymerase epsilon subunit 2

2

0

High-throughput

0.318

High

325301

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

358056

ADH1G
Alcohol dehydrogenase 1C

1

0

High-throughput

0.279

Low

868704

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

868727

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.279

Low

868729

CERS3
Ceramide synthase 3

1

0

High-throughput

0.279

Low

868733

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

868744

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

868754

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

868757

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

868762

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

868765

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

868767

LFG2
Protein lifeguard 2

1

0

High-throughput

0.279

Low

868742

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

868782

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

868804

INSI2
Insulin-induced gene 2 protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025