HitPredict

Interactor 1: TERF1 (P54274)
Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1)
Gene: TERF1

Interactor 2: TERF2 (Q15554)
Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
Gene: TERF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 20811636, 15316005
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Myb_DNA-binding~Myb_DNA-binding, TRF~TRF
Common GO terms GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000783 - nuclear telomere cap complex
GO:0003691 - double-stranded telomeric DNA binding
GO:0003720 - telomerase activity
and 15 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 439
Hs

1 542
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024