Protein: S6A11
Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Solute carrier family 6 member 11)

Gene: S6A11, SLC6A11
Organism: Homo sapiens
Interactions: 138
UniProt ID: P48066

Gene Ontology (top 5):
GO:0005332 - gamma-aminobutyric acid:sodium:chloride symporter activity
GO:0005369 - taurine:sodium symporter activity
GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0008028 - monocarboxylic acid transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

869561

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

9

High-throughput

0.575

High

870211

S6A12
Sodium- and chloride-dependent betaine transporter

1

9

High-throughput

0.575

High

870353

SC6A3
Sodium-dependent dopamine transporter

1

9

High-throughput

0.575

High

193690

TPSN
Tapasin

1

3

High-throughput

0.514

High

50511

HACL2
2-hydroxyacyl-CoA lyase 2

1

2

High-throughput

0.445

High

161203

EI24
Etoposide-induced protein 2.4 homolog

1

5

High-throughput

0.445

High

178539

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

18

High-throughput

0.445

High

181279

PGRC2
Membrane-associated progesterone receptor component 2

1

4

High-throughput

0.445

High

183137

GNPAT
Dihydroxyacetone phosphate acyltransferase

1

1

High-throughput

0.445

High

184141

RER1
Protein RER1

1

2

High-throughput

0.445

High

184408

SURF4
Surfeit locus protein 4

1

4

High-throughput

0.445

High

186414

TM9S1
Transmembrane 9 superfamily member 1

1

7

High-throughput

0.445

High

226475

SNG3
Synaptogyrin-3

1

3

High-throughput

0.445

High

248571

FADS1
Acyl-CoA

1

3

High-throughput

0.445

High

344461

STR3N
STARD3 N-terminal-like protein

1

3

High-throughput

0.445

High

469027

SRPRA
Signal recognition particle receptor subunit alpha

1

2

High-throughput

0.445

High

471629

CY1
Cytochrome c1, heme protein, mitochondrial

1

1

High-throughput

0.445

High

522619

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

6

High-throughput

0.445

High

548437

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.445

High

596620

NCPR
NADPH--cytochrome P450 reductase

1

4

High-throughput

0.445

High

609621

LEG3
Galectin-3

1

8

High-throughput

0.445

High

648265

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

1

High-throughput

0.445

High

693394

CERS1
Ceramide synthase 1

1

13

High-throughput

0.445

High

698474

CALX
Calnexin

1

17

High-throughput

0.445

High

701770

ABCD3
ATP-binding cassette sub-family D member 3

1

9

High-throughput

0.445

High

789874

FDFT
Squalene synthase

1

1

High-throughput

0.445

High

813028

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.445

High

863435

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

1

High-throughput

0.445

High

870342

RAB13
Ras-related protein Rab-13

1

5

High-throughput

0.445

High

870344

DGKE
Diacylglycerol kinase epsilon

1

7

High-throughput

0.445

High

870350

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.445

High

870352

AT2C1
Calcium-transporting ATPase type 2C member 1

1

5

High-throughput

0.445

High

870354

KDSR
3-ketodihydrosphingosine reductase

1

10

High-throughput

0.445

High

870356

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

8

High-throughput

0.445

High

870357

PTK7
Inactive tyrosine-protein kinase 7

1

7

High-throughput

0.445

High

870358

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

6

High-throughput

0.445

High

870360

TMED2
Transmembrane emp24 domain-containing protein 2

1

3

High-throughput

0.445

High

870361

DHC24
Delta(24)-sterol reductase

1

4

High-throughput

0.445

High

870362

TRAM1
Translocating chain-associated membrane protein 1

1

13

High-throughput

0.445

High

870365

MBOA5
Lysophospholipid acyltransferase 5

1

1

High-throughput

0.445

High

870366

LCLT1
Lysocardiolipin acyltransferase 1

1

13

High-throughput

0.445

High

870368

QSOX2
Sulfhydryl oxidase 2

1

8

High-throughput

0.445

High

870369

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

1

High-throughput

0.445

High

870370

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

2

High-throughput

0.445

High

870371

GALT7
N-acetylgalactosaminyltransferase 7

1

8

High-throughput

0.445

High

870373

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.445

High

870376

K2013
Uncharacterized protein KIAA2013

1

1

High-throughput

0.445

High

870377

AN13A
Ankyrin repeat domain-containing protein 13A

1

4

High-throughput

0.445

High

870380

GHDC
GH3 domain-containing protein

1

2

High-throughput

0.445

High

870381

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.445

High

870383

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

1

High-throughput

0.445

High

870385

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.445

High

870387

ATAD1
Outer mitochondrial transmembrane helix translocase

1

3

High-throughput

0.445

High

870390

SPP
Signal peptide peptidase

1

3

High-throughput

0.445

High

870391

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.445

High

870392

NAT14
Probable N-acetyltransferase 14

1

5

High-throughput

0.445

High

870394

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

1

High-throughput

0.445

High

870395

GPI8
GPI-anchor transamidase

1

1

High-throughput

0.445

High

870398

F241B
Protein FAM241B

1

1

High-throughput

0.445

High

870399

CERS2
Ceramide synthase 2

1

13

High-throughput

0.445

High

870400

S35E1
Solute carrier family 35 member E1

1

1

High-throughput

0.445

High

870401

CLP1L
Lipid scramblase CLPTM1L

1

7

High-throughput

0.445

High

870402

PIGS
GPI-anchor transamidase component PIGS

1

2

High-throughput

0.445

High

870403

SEC62
Translocation protein SEC62

1

3

High-throughput

0.445

High

870404

SORT
Sortilin

1

2

High-throughput

0.445

High

870405

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

18

High-throughput

0.445

High

870407

ESYT1
Extended synaptotagmin-1

1

6

High-throughput

0.445

High

870408

YIPF4
Protein YIPF4

1

2

High-throughput

0.445

High

870412

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.445

High

870413

YIPF3
Protein YIPF3

1

5

High-throughput

0.445

High

870417

TMT1A
Thiol S-methyltransferase TMT1A

1

3

High-throughput

0.445

High

870419

VEZA
Vezatin

1

1

High-throughput

0.445

High

870420

GBA2
Non-lysosomal glucosylceramidase

1

1

High-throughput

0.445

High

870421

SEC12
Guanine nucleotide-exchange factor SEC12

1

2

High-throughput

0.445

High

870422

AT131
Endoplasmic reticulum transmembrane helix translocase

1

2

High-throughput

0.445

High

870423

TM9S3
Transmembrane 9 superfamily member 3

1

7

High-throughput

0.445

High

870424

JPH1
Junctophilin-1

1

2

High-throughput

0.445

High

870425

APMAP
Adipocyte plasma membrane-associated protein

1

1

High-throughput

0.445

High

870427

OCAD1
OCIA domain-containing protein 1

1

3

High-throughput

0.445

High

870428

T161A
Transmembrane protein 161A

1

3

High-throughput

0.445

High

870432

SEC63
Translocation protein SEC63 homolog

1

6

High-throughput

0.445

High

870433

JAG2
Protein jagged-2

1

1

High-throughput

0.445

High

870434

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

3

High-throughput

0.445

High

870436

SRPRB
Signal recognition particle receptor subunit beta

1

4

High-throughput

0.445

High

870439

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

3

High-throughput

0.445

High

105543

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

559907

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.426

High

870347

CD81
CD81 antigen

1

0

High-throughput

0.426

High

870355

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.426

High

870359

ERG1
Squalene monooxygenase

1

0

High-throughput

0.426

High

870388

CHSTE
Carbohydrate sulfotransferase 14

1

0

High-throughput

0.426

High

870429

FKB11
Peptidyl-prolyl cis-trans isomerase FKBP11

1

0

High-throughput

0.426

High

85352

GPHRA
Golgi pH regulator A

1

7

High-throughput

0.407

High

117720

S35U4
SLC35A4 upstream open reading frame protein

1

1

High-throughput

0.407

High

170696

CLGN
Calmegin

1

17

High-throughput

0.407

High

184974

SPTC2
Serine palmitoyltransferase 2

1

4

High-throughput

0.407

High

219285

B4GA1
Beta-1,4-glucuronyltransferase 1

1

2

High-throughput

0.407

High

270004

XYLK
Glycosaminoglycan xylosylkinase

1

1

High-throughput

0.407

High

350534

CF047
Uncharacterized protein C6orf47

1

2

High-throughput

0.407

High

353926

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

1

High-throughput

0.407

High

847382

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

2

High-throughput

0.407

High

870343

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

3

High-throughput

0.407

High

870345

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

1

High-throughput

0.407

High

870346

SYJ2B
Synaptojanin-2-binding protein

1

19

High-throughput

0.407

High

870349

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

1

High-throughput

0.407

High

870351

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.407

High

870363

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

1

High-throughput

0.407

High

870364

RABL3
Rab-like protein 3

1

13

High-throughput

0.407

High

870367

HACD2
Very-long-chain

1

3

High-throughput

0.407

High

870372

SCD5
Stearoyl-CoA desaturase 5

1

1

High-throughput

0.407

High

870374

RETR3
Reticulophagy regulator 3

1

4

High-throughput

0.407

High

870375

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

8

High-throughput

0.407

High

870378

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

3

High-throughput

0.407

High

870379

CP4X1
Cytochrome P450 4X1

1

2

High-throughput

0.407

High

870382

CERS5
Ceramide synthase 5

1

13

High-throughput

0.407

High

870384

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

2

High-throughput

0.407

High

870386

XXLT1
Xyloside xylosyltransferase 1

1

1

High-throughput

0.407

High

870393

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.407

High

870396

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

1

High-throughput

0.407

High

870397

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

2

High-throughput

0.407

High

870406

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

2

High-throughput

0.407

High

870411

TMED9
Transmembrane emp24 domain-containing protein 9

1

3

High-throughput

0.407

High

870414

5NT3A
Cytosolic 5'-nucleotidase 3A

1

3

High-throughput

0.407

High

870415

SNX25
Sorting nexin-25

1

12

High-throughput

0.407

High

870418

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

1

High-throughput

0.407

High

870426

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

13

High-throughput

0.407

High

870430

CNIH4
Protein cornichon homolog 4

1

4

High-throughput

0.407

High

870431

HACD3
Very-long-chain

1

4

High-throughput

0.407

High

870435

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.407

High

870437

SNX14
Sorting nexin-14

1

12

High-throughput

0.407

High

870438

SNX13
Sorting nexin-13

1

12

High-throughput

0.407

High

155553

NEMP1
Nuclear envelope integral membrane protein 1

1

0

High-throughput

0.232

Low

402342

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.232

Low

870348

ROMO1
Reactive oxygen species modulator 1

1

0

High-throughput

0.232

Low

870389

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.232

Low

870409

RN126
E3 ubiquitin-protein ligase RNF126

1

0

High-throughput

0.232

Low

870410

FICD
Protein adenylyltransferase FICD

1

0

High-throughput

0.232

Low

870416

REEP4
Receptor expression-enhancing protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025