Interactor 1: PMS2 (P54278)
Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2)
Gene: PMS2

Interactor 2: FANCJ (Q9BX63)
Fanconi anemia group J protein (EC 3.6.4.12) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)
Gene: BRIP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 26496610, 17148452, 22968820, 34591612, 20978114, 17581638
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016887 - ATP hydrolysis activity
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 862
Hs

1 1249
+ Hs
+ Hs

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Last updated: 15 Jul 2024