Interactor 1: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Interactor 2: PRS4 (P62191)
26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene: PSMC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 26496610, 30425250, 31901637, 31740976, 19615732
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Prot_ATP_ID_OB~UCH
Common GO terms GO:0000502 - proteasome complex
GO:0005829 - cytosol
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 494
Hs

1 440
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp
+ Hs
+ Sc
+ Dm
+ Sc
+ Sc
+ Sc
+ Zm

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Last updated: 15 Jul 2024