HitPredict

Interactor 1: AAPK1 (P54645)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: Prkaa1

Interactor 2: 1433E (P62260)
14-3-3 protein epsilon (14-3-3E) (Mitochondrial import stimulation factor L subunit) (MSF L)
Gene: Ywhae

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	24625528
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0030424 - axon GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Rn			1 255
+	Hs
		909507 AAPK1_HUMAN (1-559): 0: 586: 99.11		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		871354 AAPK2_HUMAN (12-559): 0: 531: 75.09		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Xl
		223345 Q8QGV3_XENLA (3-545): 1.37e-147: 445: 30.38		O57468_XENLA (1-255): 1.7e-152: 426: 96.47
+	Hs
		909730 MARK2_HUMAN (19-545): 5.78e-146: 441: 30.13		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910234 MARK2_MOUSE (19-545): 3.64e-145: 439: 29.76		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		647862 MARK3_HUMAN (2-536): 1.6e-143: 434: 28.57		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		883214 SIK1_HUMAN (4-401): 1.93e-142: 431: 38.21		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910231 MARK3_MOUSE (11-536): 2.47e-142: 430: 28.50		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Xl
		223344 Q804T2_XENLA (2-536): 4.53e-142: 429: 28.77		O57468_XENLA (1-255): 1.7e-152: 426: 96.47
+	Mm
		910266 NUAK1_MOUSE (6-538): 4.12e-141: 424: 28.33		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	At
		965360 CIPKC_ARATH (8-530): 1.22e-147: 435: 25.29		14332_ARATH (4-255): 1.05e-147: 414: 74.41
+	At
		788672 CIPKC_ARATH (8-530): 1.22e-147: 435: 25.29		14333_ARATH (1-253): 3.45e-147: 413: 74.12
+	At
		1280891 CIPKC_ARATH (8-530): 1.22e-147: 435: 25.29		14337_ARATH (2-255): 7.73e-147: 412: 71.21
+	Mm
		910308 MARK4_MOUSE (11-404): 1.69e-133: 408: 35.56		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		909916 MARK4_HUMAN (11-404): 4.53e-133: 406: 35.31		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Sc
		419854 SNF1_YEAST (23-475): 3.93e-140: 421: 38.25		BMH2_YEAST (4-242): 1.14e-134: 382: 77.08
+	Sc
		419824 SNF1_YEAST (23-475): 3.93e-140: 421: 38.25		BMH1_YEAST (2-243): 2.43e-134: 381: 75.72
+	Hs
		910013 SIK2_HUMAN (10-340): 2.08e-85: 285: 42.69		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909786 BRSK2_HUMAN (24-376): 7.32e-82: 272: 42.12		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910272 BRSK2_MOUSE (24-376): 9.31e-82: 272: 42.12		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00