HitPredict

Interactor 1: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Interactor 2: RNF34 (Q969K3)
E3 ubiquitin-protein ligase RNF34 (EC 2.3.2.27) (Caspase regulator CARP1) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (RING finger protein 34) (RING finger protein RIFF) (RING-type E3 ubiquitin transferase RNF34)
Gene: RNF34

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	24981860, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 372
+	Hs
		504525 HSP7C_HUMAN (3-616): 0: 946: 87.95		RNF34_HUMAN (1-372): 3.26e-134: 389: 100.00
+	Hs
		871704 HSP72_HUMAN (1-639): 0: 955: 100.00		RFFL_HUMAN (8-372): 4.67e-111: 330: 42.78
+	Hs
		564139 HSP76_HUMAN (2-639): 0: 945: 77.45		RFFL_HUMAN (8-372): 4.67e-111: 330: 42.78
+	Hs
		282501 HSP7C_HUMAN (3-616): 0: 946: 87.95		RNF8_HUMAN (155-366): 3.49e-31: 125: 15.55
+	Hs
		504031 HSP7C_HUMAN (3-616): 0: 946: 87.95		BIRC3_HUMAN (247-372): 2e-26: 112: 24.03
+	Dm
		669792 HSP7A_DROME (6-639): 0: 945: 78.72		DIAP2_DROME (266-372): 6.67e-22: 98.9: 20.54
+	Dm
		505058 HSP7D_DROME (3-615): 0: 930: 83.36		DIAP2_DROME (266-372): 6.67e-22: 98.9: 20.54
+	Dr
		1157472 Q6NYR4_DANRE (3-617): 0: 938: 86.99		MIB1_DANRE (313-366): 2.26e-11: 67.6: 31.48