HitPredict

Interactor 1: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Interactor 2: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 363 Hs			1 128
+	Hs
		872136 RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		474969 RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00
+	At
		1091733 RD23C_ARATH (3-363): 1.8e-100: 305: 33.25		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1091732 RD23D_ARATH (3-363): 1.55e-99: 301: 31.23		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Sp
		251961 RHP23_SCHPO (3-363): 2.02e-78: 247: 33.25		RL402_SCHPO (1-128): 3.96e-53: 164: 90.63
+	Sc
		477610 RAD23_YEAST (3-361): 1e-75: 240: 28.57		RL40A_YEAST (1-128): 1.32e-53: 166: 89.84
+	Dm
		547941 Q9V3W9_DROME (3-362): 9.91e-87: 269: 38.43		RS27A_DROME (1-77): 3.98e-38: 127: 98.70
+	Dm
		574854 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		RL40_DROME (1-128): 2.2e-56: 173: 97.66
+	Sp
		251959 RHP23_SCHPO (3-363): 2.02e-78: 247: 33.25		RS27A_SCHPO (1-71): 1.27e-32: 113: 95.78
+	Pf
		1181547 Q8IJS8_PLAF7 (3-362): 2.53e-72: 232: 24.37		Q7KQK2_PLAF7 (1-76): 1.15e-31: 117: 98.68
+	Hs
		924435 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Hs
		924430 UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Dm
		1362837 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		Q9W418_DROME (1-77): 1.45e-41: 145: 98.70
+	Dm
		547946 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		RS27A_DROME (1-77): 3.98e-38: 127: 98.70
+	Hs
		924216 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		924208 UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		1137416 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		Q5U5U6_HUMAN (1-76): 1.52e-33: 118: 100.00
+	Hs
		1286323 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		Q96C32_HUMAN (1-77): 1.06e-32: 118: 98.70
+	Hs
		475241 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00
+	Hs
		475223 UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00