HitPredict

Interactor 1: EPHB2 (P54763)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: GRIP1 (Q925T6)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.42 1.00 0.653

The method score is based on:

Property Details
Experiments 9883737
Identification Methods two hybrid, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~fn3, PDZ~SAM_1
Common GO terms GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0030425 - dendrite
GO:0042734 - presynaptic membrane
GO:0043025 - neuronal cell body
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 986
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024