HitPredict

Interactor 1: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20595233
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0030466 - silent mating-type cassette heterochromatin formation
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 914 Sc			1 134
+	Sc
		392178 ORC1_YEAST (1-914): 0: 798: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392528 ORC1_YEAST (1-914): 0: 798: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Sc
		392015 SIR3_YEAST (1-914): 0: 587: 26.50		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392240 SIR3_YEAST (1-914): 0: 587: 26.50		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		1033386 ORC1_HUMAN (155-908): 9.77e-118: 381: 21.21		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Sc
		392530 ORC4_YEAST (385-711): 1.69e-45: 174: 13.51		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		875272 TERA_HUMAN (420-667): 3.72e-25: 114: 10.00		H2AJ_HUMAN (7-134): 1.86e-52: 163: 55.81
+	Hs
		875054 TERA_HUMAN (420-667): 3.72e-25: 114: 10.00		H2AV_HUMAN (10-134): 1.67e-40: 133: 67.72
+	Hs
		469960 RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391577 RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83