HitPredict

Interactor 1: TMEDA (P54837)
Endoplasmic reticulum vesicle protein 25
Gene: ERV25

Interactor 2: ERV41 (Q04651)
ER-derived vesicles protein ERV41
Gene: ERV41

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	37968396, 28183979
Identification Methods	affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0030134 - COPII-coated ER to Golgi transport vesicle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 211 Sc			1 352
+	Hs
		1071860 TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90		ERGI3_HUMAN (1-334): 2.53e-133: 387: 23.20
+	Sc
		980047 ERP1_YEAST (4-211): 6.24e-52: 168: 15.91		ERV41_YEAST (1-352): 1.51e-143: 411: 100.00
+	Sc
		763784 TMEDA_YEAST (1-211): 1.73e-63: 197: 100.00		ERV46_YEAST (2-335): 2.8e-109: 326: 18.78
+	Hs
		1071816 TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90		ERGI2_HUMAN (1-320): 2.32e-109: 325: 27.96
+	Sc
		698463 EMP24_YEAST (33-211): 6.48e-24: 95.9: 19.23		ERV41_YEAST (1-352): 1.51e-143: 411: 100.00
+	Sc
		763793 ERP1_YEAST (4-211): 6.24e-52: 168: 15.91		ERV46_YEAST (2-335): 2.8e-109: 326: 18.78
+	Hs
		1071805 TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90		ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72
+	Hs
		833291 TMEDA_HUMAN (18-211): 3.7e-62: 194: 37.25		ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72
+	Hs
		1282678 TMED5_HUMAN (14-209): 2.87e-52: 169: 15.20		ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72
+	Sc
		698414 EMP24_YEAST (33-211): 6.48e-24: 95.9: 19.23		ERV46_YEAST (2-335): 2.8e-109: 326: 18.78