Interactor 1: P5CS (P54886)
Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]
Gene: ALDH18A1

Interactor 2: P5CS (P54886)
Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]
Gene: ALDH18A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37071682
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_kinase~AA_kinase, Aldedh~Aldedh
Common GO terms GO:0003723 - RNA binding
GO:0004349 - glutamate 5-kinase activity
GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
and 8 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 795
Hs

1 795
+ Dm
+ At
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024