HitPredict

Interactor 1: P5CS (P54886)
Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]
Gene: ALDH18A1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 795 Hs			1 779
+	Hs
		873407 P5CS_HUMAN (1-795): 0: 1040: 100.00		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		873452 P5CS_HUMAN (1-795): 0: 1040: 100.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		787148 P5CS_HUMAN (1-795): 0: 1040: 100.00		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27
+	Hs
		396502 ALDH2_HUMAN (326-763): 3.36e-125: 386: 14.69		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		296381 AL1A2_HUMAN (326-763): 1.02e-122: 380: 13.88		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		676711 AL1B1_HUMAN (326-763): 3.11e-121: 376: 14.90		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		848960 AL3A2_HUMAN (363-761): 5.3e-119: 369: 16.10		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		814391 AL1A3_HUMAN (323-763): 5.55e-133: 406: 16.43		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21