Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: UBX2B (Q14CS0)
UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37)
Gene: UBXN2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 26186194, 26389662, 28514442, 29997244, 33058883, 33961781, 25416956, 25775548, 29599191, 30344098, 32296183, 35271311, 18775313, unassigned1304
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, pull down, two hybrid, luminescence based mammalian interactome mapping, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC48_2~UBX, CDC48_N~UBX
Common GO terms GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 806
Hs

1 331
+ Rn
+ Rn
+ Hs
+ Mm
+ Hs
+ Rn
+ Sc
+ At
+ Dm
+ Sp
+ Ce

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Last updated: 15 Jul 2024