HitPredict

Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	27545878, 24726327, 24726323
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography, unspecified method
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0036435 - K48-linked polyubiquitin modification-dependent protein binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 1072
+	Mm
		967688 TERA_MOUSE (1-806): 0: 749: 100.00		RNF31_MOUSE (1-1072): 0: 1083: 85.54
+	Hs
		875476 TERA_HUMAN (1-806): 0: 749: 100.00		ARI1_HUMAN (600-1058): 1.52e-114: 367: 13.84
+	Hs
		312526 TERA_HUMAN (1-806): 0: 749: 100.00		ARI2_HUMAN (654-1044): 9.03e-91: 301: 15.84
+	Hs
		875357 TERA_HUMAN (1-806): 0: 749: 100.00		RN19A_HUMAN (698-946): 5.63e-54: 205: 21.21
+	Mm
		841457 TERA_MOUSE (1-806): 0: 749: 100.00		RN19A_MOUSE (698-946): 1.31e-44: 176: 21.21
+	Hs
		875401 TERA_HUMAN (1-806): 0: 749: 100.00		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		177515 NVL_HUMAN (426-801): 5.22e-61: 223: 25.77		CUL9_HUMAN (622-1043): 1.8e-86: 309: 16.09