Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: SELS (Q9BQE4)
Selenoprotein S (SelS) (VCP-interacting membrane protein)
Gene: SELENOS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.933

The method score is based on:

Property Details
Experiments 26549226, 26504085, 29599191, 29540532, 18199748, 35271311, 17872946, 22119785, 24424410, 25008318, 24700463, 15215856, 16289116, 21832065
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC48_2~Selenoprotein_S, CDC48_N~Selenoprotein_S
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
and 3 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024