Protein: CISD2
CDGSH iron-sulfur domain protein (CDGSH iron-sulfur domain-containing protein-2 homolog)

Gene: CISD2, Cisd
Organism: Drosophila melanogaster
Interactions: 70
UniProt ID: Q9VAM6

Gene Ontology (top 5):
GO:0005741 - mitochondrial outer membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0006839 - mitochondrial transport
GO:0006879 - intracellular iron ion homeostasis
GO:0010506 - regulation of autophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1378868

Q960D4
SD06560p

2

1

High-throughput

0.571

High

1468140

Q9VZL3
very-long-chain enoyl-CoA reductase

2

1

High-throughput

0.571

High

1375310

VDAC
Voltage-dependent anion-selective channel

2

0

High-throughput

0.547

High

197092

O18332
FI01544p

2

2

High-throughput

0.521

High

52689

A1Z729
NADP-retinol dehydrogenase

1

1

High-throughput

0.479

High

53426

A1Z7S3
Rab32, isoform B

1

6

Small-scale

0.479

High

1377360

Q95RF6
LD34461p

1

1

High-throughput

0.479

High

1468141

Q9W0M4
Endoplasmic reticulum transmembrane protein

1

2

High-throughput

0.479

High

55202

A1Z992
1,4-alpha-glucan branching enzyme

1

0

Small-scale

0.458

High

118543

M9NEX3
Cytochrome b5

1

0

High-throughput

0.458

High

1468124

Q9VCV4
Cytoplasmic aconitate hydratase

1

0

Small-scale

0.458

High

86541

B9EQV3
Endoplasmic reticulum transmembrane protein

1

2

High-throughput

0.445

High

1267393

Q7KLX3
Translocon-associated protein subunit delta

1

1

High-throughput

0.445

High

1468145

Q9W4N8
LD30122p

1

2

High-throughput

0.445

High

304244

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.426

High

1176808

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.426

High

1321689

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

1468131

Q9VKM7
AT01533p

1

0

High-throughput

0.426

High

1468132

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.426

High

1468136

Q9VUZ0
Translocon-associated protein subunit beta

1

0

High-throughput

0.426

High

197356

O18335
Rab11

1

3

High-throughput

0.407

High

565018

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

2

High-throughput

0.407

High

614936

SYB
Synaptobrevin

1

1

High-throughput

0.407

High

663989

PHB1
Prohibitin 1

1

1

High-throughput

0.407

High

829664

ARF4
ADP ribosylation factor 4

1

3

High-throughput

0.407

High

875266

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

958887

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.407

High

1236883

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

1264527

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.407

High

1265818

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.407

High

1378472

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.407

High

1378827

Q960C7
NADP-retinol dehydrogenase

1

1

High-throughput

0.407

High

1465603

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.407

High

1468125

Q9VD29
small monomeric GTPase

1

7

High-throughput

0.407

High

1468128

ARL8
ADP-ribosylation factor-like protein 8

1

4

High-throughput

0.407

High

1468137

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

1

High-throughput

0.407

High

1468144

Q9W3N1
RH59310p

1

3

High-throughput

0.407

High

1306119

Q8IRD3
Glutathione peroxidase

2

0

High-throughput

0.298

High

1465367

KRH2
Krueppel homolog 2

2

0

High-throughput

0.298

High

52804

A1Z792
Uncharacterized protein, isoform B

1

0

High-throughput

0.249

Low

1468130

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1468134

ORCO
Odorant receptor coreceptor

1

0

Small-scale

0.249

Low

1468142

Q9W0Q9
Uncharacterized protein, isoform A

1

0

High-throughput

0.249

Low

57609

A1ZB71
Glutathione S transferase E6

1

0

High-throughput

0.232

Low

715141

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

875006

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.232

Low

1070790

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

1173067

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.232

Low

1173567

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.232

Low

1174140

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.232

Low

1174234

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.232

Low

1176092

DX39B
ATP-dependent RNA helicase WM6

1

0

High-throughput

0.232

Low

1176308

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

0

High-throughput

0.232

Low

1197335

Q500Y7
GEO11443p1

1

0

High-throughput

0.232

Low

1237022

Q6NP72
GEO09659p1

1

0

High-throughput

0.232

Low

1237581

Q6NR46
Serine palmitoyltransferase 1

1

0

High-throughput

0.232

Low

1268174

Q7KN94
Electron transfer flavoprotein subunit alpha

1

0

High-throughput

0.232

Low

1305737

Q8IQZ7
FI19014p1

1

0

High-throughput

0.232

Low

1321601

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.232

Low

1440573

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.232

Low

1466740

Q9V9Q4
LD43819p

1

0

High-throughput

0.232

Low

1468123

Q9VAY2
Heat shock protein 83

1

0

High-throughput

0.232

Low

1468126

Q9VGK3
peptidylprolyl isomerase

1

0

High-throughput

0.232

Low

1468127

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.232

Low

1468129

Q9VHX9
alpha-glucosidase

1

0

High-throughput

0.232

Low

1468133

Q9VN44
FI07923p

1

0

High-throughput

0.232

Low

1468135

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1468138

Q9VWL0
Mec2

1

0

High-throughput

0.232

Low

1468139

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

0

High-throughput

0.232

Low

1468143

ATPK
Putative ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025