HitPredict

Interactor 1: C9JXZ5 (C9JXZ5)
Vesicle-associated membrane protein 8 (Endobrevin)
Gene: VAMP8

Interactor 2: STX7 (O15400)
Syntaxin-7
Gene: STX7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0019905 - syntaxin binding GO:0031201 - SNARE complex and 1 others more... GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 74 Hs			1 261
+	Dm
		1098086 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		STX1A_DROME (1-256): 1.06e-63: 202: 22.73
+	At
		955681 VA713_ARATH (1-72): 2.4e-28: 102: 26.39		SYP22_ARATH (3-245): 3.86e-59: 190: 29.63
+	Dm
		577220 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		STX1A_DROME (1-256): 1.06e-63: 202: 22.73
+	At
		955679 VA714_ARATH (1-74): 2.01e-26: 97.6: 31.08		SYP22_ARATH (3-245): 3.86e-59: 190: 29.63
+	At
		955702 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP22_ARATH (3-245): 3.86e-59: 190: 29.63
+	At
		221561 VA711_ARATH (1-72): 3.78e-23: 89.2: 30.56		SYP22_ARATH (3-245): 3.86e-59: 190: 29.63
+	At
		221563 VA711_ARATH (1-72): 3.78e-23: 89.2: 30.56		SYP21_ARATH (4-245): 2.26e-55: 180: 32.25
+	At
		249598 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP41_ARATH (3-256): 3.55e-53: 176: 22.09
+	At
		1352876 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP43_ARATH (3-256): 2.67e-52: 174: 20.16
+	At
		1352985 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP42_ARATH (2-256): 4.79e-52: 174: 20.61
+	At
		1378372 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY121_ARATH (7-239): 7.67e-52: 174: 18.15
+	At
		812702 VA722_ARATH (1-73): 4.73e-23: 88.8: 36.99		SY121_ARATH (7-239): 7.67e-52: 174: 18.15
+	At
		1352937 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY122_ARATH (13-239): 1.79e-49: 167: 20.50
+	Dm
		1178101 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		Q7K0X9_DROME (10-256): 4.5e-44: 152: 38.85
+	Dm
		1178134 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		Q9VU45_DROME (10-260): 1.85e-43: 150: 23.41
+	Dm
		577226 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		Q7K0X9_DROME (10-256): 4.5e-44: 152: 38.85
+	Dm
		577255 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		Q9VU45_DROME (10-260): 1.85e-43: 150: 23.41
+	Dm
		1178130 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		Q9VR90_DROME (149-246): 5.68e-13: 69.7: 41.84
+	Dm
		577251 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		Q9VR90_DROME (149-246): 5.68e-13: 69.7: 41.84
+	At
		1258650 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY132_ARATH (94-239): 1.06e-11: 65.5: 31.51