HitPredict

Interactor 1: C9JXZ5 (C9JXZ5)
Vesicle-associated membrane protein 8 (Endobrevin)
Gene: VAMP8

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0031201 - SNARE complex GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 74 Hs			1 276
+	Dm
		1098086 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	Dm
		577220 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	At
		955681 VA713_ARATH (1-72): 2.4e-28: 102: 26.39		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	At
		955679 VA714_ARATH (1-74): 2.01e-26: 97.6: 31.08		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	At
		1352985 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP42_ARATH (2-273): 1.6e-59: 193: 21.79
+	At
		1378372 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY121_ARATH (8-252): 2.96e-59: 193: 18.75
+	At
		955702 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	At
		221561 VA711_ARATH (1-72): 3.78e-23: 89.2: 30.56		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	At
		249598 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP41_ARATH (2-273): 4.62e-58: 189: 21.07
+	At
		1352937 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY122_ARATH (1-252): 6.92e-57: 187: 20.53
+	At
		1352876 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SYP43_ARATH (2-273): 2.11e-55: 183: 20.00
+	Dm
		1178101 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	At
		221563 VA711_ARATH (1-72): 3.78e-23: 89.2: 30.56		SYP21_ARATH (1-258): 7.63e-55: 180: 27.88
+	Dm
		577226 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	At
		1114744 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY111_ARATH (4-252): 1.64e-51: 172: 19.77
+	Dm
		1178134 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	Dm
		577255 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	At
		1258650 VA721_ARATH (1-73): 6.59e-24: 91.1: 38.36		SY132_ARATH (107-252): 5.34e-12: 66.6: 32.88
+	Dm
		1178130 Q7JYX5_DROME (1-74): 9.14e-25: 93: 36.49		Q9VR90_DROME (166-256): 7.07e-11: 63.5: 36.26
+	Dm
		577251 SYB_DROME (1-69): 2.94e-24: 89.9: 30.44		Q9VR90_DROME (166-256): 7.07e-11: 63.5: 36.26