HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: RAB2A (P53994)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	27507650, 28706196, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 212
+	Mm
		99942 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		RAB1A_MOUSE (3-212): 4.62e-85: 252: 45.24
+	Hs
		918932 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		RAB1A_HUMAN (3-212): 4.62e-85: 252: 45.24
+	Hs
		896668 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		RAB14_HUMAN (3-211): 3.08e-84: 250: 59.33
+	Hs
		914291 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		RB11A_HUMAN (3-212): 2.18e-83: 248: 46.67
+	Hs
		895014 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		RAB4B_HUMAN (3-188): 5.16e-71: 216: 55.91
+	Hs
		895006 DAB2P_HUMAN (97-1339): 0: 859: 47.63		RAB4B_HUMAN (3-188): 5.16e-71: 216: 55.91
+	Hs
		895315 NGAP_HUMAN (84-1338): 0: 800: 43.48		RAB2A_HUMAN (1-212): 2.4e-88: 260: 98.59
+	Hs
		914440 NGAP_HUMAN (84-1338): 0: 800: 43.48		RB11A_HUMAN (3-212): 2.18e-83: 248: 46.67
+	Mm
		1160701 GAPD1_MOUSE (412-1068): 7.48e-131: 440: 13.18		RAB4B_MOUSE (3-188): 3.89e-71: 217: 55.91
+	Hs
		809235 IQGA1_HUMAN (219-723): 6.44e-107: 374: 13.97		RAB2A_HUMAN (1-212): 2.4e-88: 260: 98.59