HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: SYDE1 (Q6ZW31)
Rho GTPase-activating protein SYDE1 (Synapse defective protein 1 homolog 1) (Protein syd-1 homolog 1)
Gene: SYDE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 735
+	Hs
		876410 AFAD_HUMAN (1-1824): 0: 1279: 100.00		RHG21_HUMAN (10-703): 9.42e-90: 310: 14.71
+	Hs
		506555 AFAD_HUMAN (1-1824): 0: 1279: 100.00		BCR_HUMAN (1-598): 7.89e-90: 308: 21.94
+	Hs
		253330 AFAD_HUMAN (1-1824): 0: 1279: 100.00		SRGP2_HUMAN (114-734): 6.4e-87: 297: 12.74
+	Hs
		64675 AFAD_HUMAN (1-1824): 0: 1279: 100.00		RHG32_HUMAN (281-651): 6.17e-66: 240: 20.90
+	Hs
		1173153 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		SYDE1_HUMAN (1-735): 1.78e-178: 529: 100.00
+	Hs
		253413 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		SRGP2_HUMAN (114-734): 6.4e-87: 297: 12.74
+	Hs
		1343640 KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64		STA13_HUMAN (269-563): 2.44e-68: 245: 22.40
+	Hs
		1138024 GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72		SYDE2_HUMAN (93-713): 8.07e-98: 329: 38.25
+	Mm
		1131438 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		ABR_MOUSE (1-606): 2.93e-108: 351: 21.77
+	Hs
		231412 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		SRGP2_HUMAN (114-734): 6.4e-87: 297: 12.74
+	Hs
		231773 KIF1B_HUMAN (191-589): 6.21e-42: 171: 15.66		STA13_HUMAN (269-563): 2.44e-68: 245: 22.40
+	Mm
		1265174 LNX2_MOUSE (973-1126): 6.83e-17: 88.9: 20.38		SRGP2_MOUSE (114-734): 3.21e-88: 301: 12.74
+	Hs
		253346 PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14		SRGP2_HUMAN (114-734): 6.4e-87: 297: 12.74
+	Hs
		1133710 MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60		RHG21_HUMAN (10-703): 9.42e-90: 310: 14.71
+	Hs
		856149 RADIL_HUMAN (830-1106): 4.06e-27: 122: 18.06		CHIO_HUMAN (171-604): 8.43e-76: 254: 17.96
+	Hs
		1148381 DLG3_HUMAN (1009-1467): 4.67e-23: 109: 13.25		RHG17_HUMAN (148-721): 7.33e-76: 264: 15.04
+	Mm
		1143388 DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51		RHG32_MOUSE (281-651): 9.7e-65: 236: 20.90
+	Hs
		1148378 INADL_HUMAN (1003-1089): 2.08e-11: 71.8: 25.81		RHG17_HUMAN (148-721): 7.33e-76: 264: 15.04
+	Hs
		63075 PLEC_HUMAN (1384-1680): 9.8e-11: 69.6: 16.67		RHG42_HUMAN (416-643): 3.36e-65: 234: 29.24
+	Hs
		1246416 INADL_HUMAN (1003-1089): 2.08e-11: 71.8: 25.81		HMHA1_HUMAN (410-597): 1.75e-19: 95.9: 36.06