Interactor 1: KMT2A (P55200)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A
Interactor 2: RBBP5 (Q8BX09)
Retinoblastoma-binding protein 5 (RBBP-5)
Gene: RBBP5
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21335234 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SET~WD40 |
| Common GO terms | GO:0005634 - nucleus GO:0035097 - histone methyltransferase complex GO:0045815 - transcription initiation-coupled chromatin remodeling GO:0071339 - MLL1 complex |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
