HitPredict

Interactor 1: BRPF1 (P55201)
Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)
Gene: BRPF1

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.666

Property	Details
Experiments	21720545
Identification Methods	unspecified method, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1214 Hs			1 136
+	Hs
		876688 BRPF1_HUMAN (1-1214): 0: 1189: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		876690 BRPF1_HUMAN (1-1214): 0: 1189: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		828181 BRPF1_HUMAN (1-1214): 0: 1189: 100.00		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		1086350 BRPF3_HUMAN (58-1211): 0: 911: 48.70		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		319165 BRD1_HUMAN (62-1214): 0: 778: 44.59		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		319213 BRD1_HUMAN (62-1214): 0: 778: 44.59		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		319169 BRD1_HUMAN (62-1214): 0: 778: 44.59		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		319242 BRD1_HUMAN (62-1214): 0: 778: 44.59		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		934879 JADE1_HUMAN (74-656): 7.35e-135: 434: 25.83		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1152679 JADE1_HUMAN (74-656): 7.35e-135: 434: 25.83		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		1086329 JADE2_HUMAN (71-641): 3.11e-120: 393: 26.08		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		935056 JADE3_HUMAN (73-656): 1.19e-118: 389: 25.21		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086246 JADE3_HUMAN (73-656): 1.19e-118: 389: 25.21		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Sc
		902142 NTO1_YEAST (119-698): 3.26e-123: 399: 25.45		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Hs
		828328 JADE3_HUMAN (73-656): 1.19e-118: 389: 25.21		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		935232 KDM4C_HUMAN (71-489): 1.56e-78: 282: 24.20		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1174653 KDM4C_HUMAN (71-489): 1.56e-78: 282: 24.20		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		952622 KDM4C_HUMAN (71-489): 1.56e-78: 282: 24.20		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		301134 KDM4B_HUMAN (86-464): 9e-76: 275: 22.72		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		301136 KDM4B_HUMAN (86-464): 9e-76: 275: 22.72		H33_HUMAN (1-136): 1.59e-61: 186: 97.06