HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29509190, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 530
+	Hs
		369260 SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269746 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1074801 TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		267782 TAF5L_HUMAN (10-111): 1.27e-15: 79.4: 24.32		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369932 WDR5B_HUMAN (2-194): 1.22e-31: 122: 16.67		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		903403 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369669 TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		267731 TAF5L_HUMAN (10-111): 1.27e-15: 79.4: 24.32		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377562 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		369305 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782550 TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		488008 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		487272 SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		267744 TAF5L_HUMAN (10-111): 1.27e-15: 79.4: 24.32		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		782513 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Mm
		903664 WDR5_MOUSE (249-320): 1.4e-10: 63.3: 16.67		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		487288 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59